Comparison of the effect of Acetaminophen, Pethidine and Ibuprofen on pain relief in patients with acute cholecystitis
Phase 2
Completed
- Conditions
- Acute cholecystitis.Acute cholecystitis
- Registration Number
- IRCT201710059014N191
- Lead Sponsor
- Vice-chancellor for Research and Technology, Hamadan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Age of 18 to 75 years;
Acute cholecystitis
Exclusion Criteria
Pregnancy;
using analgesic within pass 6 hours;
Addiction to narcotic or psychedelic;
Contraindication of Acetaminophen, Pethidine, or Ibuprofen;
Chronic renal failure
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measuring severity of pain. Timepoint: before infusion and 30, 60, and 90 minutes after infusion. Method of measurement: using Visual Analog Scale (VAS).
- Secondary Outcome Measures
Name Time Method Assessing nausea and vomiting. Timepoint: before infusion and 30, 60, and 90 minutes after infusion. Method of measurement: by taking history.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the analgesic effects of Acetaminophen, Pethidine, and Ibuprofen in acute cholecystitis?
How do the analgesic effects of Acetaminophen, Pethidine, and Ibuprofen compare to standard-of-care treatments for acute cholecystitis pain?
Are there specific biomarkers that predict differential response to Acetaminophen, Pethidine, or Ibuprofen in acute cholecystitis patients?
What are the known adverse events associated with Acetaminophen, Pethidine, and Ibuprofen in acute cholecystitis management?
How do combination therapies involving Acetaminophen, Pethidine, and Ibuprofen impact pain relief in acute cholecystitis compared to monotherapies?