Palatability and Postprandial Sensations

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Other: Combined meal; Other: Mixed meal

• Registration Number: NCT03134365
• Lead Sponsor: Hospital Universitari Vall d'Hebron Research Institute

Brief Summary

Aim: to determine the effect of palatability on the cognitive (satiation/fullness) and emotive (digestive well-being/mood) responses to meal ingestion. The postprandial responses to conventional (potato and cheese cream followed by vanilla cream) versus unconventional test meals (mixture of both creams) with identical composition (350 Kcal) and physical characteristics (colour, texture, consistency, temperature) but distinctively different palatability will be studied on a cross over-design. The responses to the meals will be tested on 2 different days.

Participants (22 non-obese healthy men) will be instructed to eat a standard dinner the day before, to consume a standard breakfast at home after overnight fast, and to report to the laboratory, where the test meal will be administered 5 h after breakfast. Studies will be conducted in a quiet, isolated room with participants sitting on a chair. Perception will be measured at 5 min intervals 10 min before and 20 min after ingestion and at 10 min intervals up to 60 min after the probe meal.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08-04
• Primary Completion: 2016-11-23
• Study Completion: 2016-12-02
• Status Verified: 2017-04
• Study First Submitted: 2017-04-25
• Study First Submitted QC: 2017-04-25
• Last Update Submitted: 2017-04-25
• Study First Posted: 2017-04-28
• Last Update Posted: 2017-04-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 22

Inclusion Criteria

• non obese

Exclusion Criteria

• history of gastrointestinal symptoms
• prior obesity
• use of medications
• history of anosmia and ageusia
• current dieting
• alcohol abuse
• psychological disorders
• eating disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Combined meal	Combined meal	-
Mixed meal	Mixed meal	-

Primary Outcome Measures

Name	Time	Method
Meal palatability	1 day	Meal palatability measured by 10 score scales at the end of the test meal
Change in digestive well-being measured after the test meal	1 day	Change in average well-being measured by 10 score scales at the end of the test meal.

Secondary Outcome Measures

Name	Time	Method
Change in satiety measured after the test meal	1 day	Change in average satiety measured by 10 score scales at the end of the test meal
Change in mood measured after the test meal	1 day	Change in average mood measured by 10 score scales at the end of the test meal.
Change in fullness sensation measured after the test meal	1 day	Change in average fullness measured by 10 score scales at the end of the test meal
Change in abdominal discomfort/pain sensation measured after the test meal	1 day	Change in average abdominal discomfort/pain measured by 10 score scales at the end of the test meal

Trial Locations

Locations (1)

University Hospital Vall d'Hebron; 🇪🇸 Barcelona, Spain