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Clinical Trials/NCT00251862
NCT00251862
Completed
N/A

Shared Decision-Making for Colorectal Cancer Screening

Agency for Healthcare Research and Quality (AHRQ)2 sites in 1 country825 target enrollmentJanuary 2005

Overview

Phase
N/A
Intervention
Not specified
Conditions
Colorectal Cancer
Sponsor
Agency for Healthcare Research and Quality (AHRQ)
Enrollment
825
Locations
2
Primary Endpoint
Patient Adherence (Test Completion)
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

The overall objective of this study is to conduct a three-arm randomized controlled trial to evaluate the impact of an interactive, web-based decision aid on shared decision-making and patient adherence to colorectal cancer (CRC) screening recommendations.

Detailed Description

Colorectal cancer (CRC) is the second leading cause of cancer-related death and third most commonly diagnosed cancer among men and women in the United States. Screening has been shown to be a cost-effective strategy for reducing both CRC mortality through early detection and incidence through the detection and removal of precancerous adenomatous polyps (adenomas). Despite a compelling rationale and widespread endorsement by authoritative groups, screening rates remain far below those necessary to achieve significant reductions in CRC mortality or incidence. Poor patient acceptance and non-adherence to screening recommendations are partly responsible for low screening rates. Shared decision-making has been advocated as a potentially effective yet unproven strategy for addressing this problem. Implicit in this approach is the need for an unbiased decision aid that not only educates patients about the pros and cons of the different strategies so as to enable them to identify a preferred strategy but also empowers patients to take a proactive role in the decision-making process, thereby increasing satisfaction and promoting adherence. From a logistical standpoint, the decision aid must also be easy to implement in the ambulatory setting so as to maximize use but minimize demands on physician time and office resources. To address this need, we have developed an interactive, web-based decision aid and implementation strategy for use in routine clinical practice. Comparison(s): Average risk subjects assigned to one of two intervention arms (decision aid alone versus decision aid plus personalized risk assessment with feedback) compared to a control arm(generic website that discusses lifestyle changes that can reduce overall cancer risk).

Registry
clinicaltrials.gov
Start Date
January 2005
End Date
December 2010
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Agency for Healthcare Research and Quality (AHRQ)
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Asymptomatic average-risk subjects
  • Under the direct care of one of participating site's staff (attending) physicians or physician extenders;
  • No prior screening other than fecal occult blood testing (FOBT);
  • No major co-morbidities that preclude CRC screening by any method

Exclusion Criteria

  • Prior CRC screening by any method other than FOBT occult blood testing
  • High-risk condition (personal history of colorectal cancer or polyps, family history of colorectal cancer or polyps involving one or more first degree relatives, chronic inflammatory bowel disease)
  • Lack of fluency in written and spoken English (since decision aid and personalized risk assessment tool will be in English only due to funding issues);
  • Comorbidities that preclude CRC screening by any method

Outcomes

Primary Outcomes

Patient Adherence (Test Completion)

Time Frame: 12 months post-intervention

Completion of a screening test within 12 months of the study visit.

Secondary Outcomes

  • Patient Knowledge(Immediate post-intervention study visit)
  • Patient Satisfaction With Decision Making Process(Immediate post-intervention primary care provider (PCP) visit)
  • Screening Intentions(Immediate post-intervention study visit)

Study Sites (2)

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