Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars

Not Applicable

Not yet recruiting

• Conditions: Bone Volume; Immediate Implant With Bone Graft

• Registration Number: NCT06962878
• Lead Sponsor: Cairo University

Brief Summary

Twenty recruited patients indicated for immediate implant placement in mandibular molar sites are divided into two groups, with each group containing ten patients. One group assigned for placement of xenograft after molar extraction and immediate implant placement, while the other group received allograft as space-filling material.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-04-30
• Study First Submitted QC: 2025-04-30
• Status Verified: 2025-05
• Study First Posted: 2025-05-08
• Last Update Submitted: 2025-06-04
• Study Start: 2025-06-06
• Last Update Posted: 2025-06-06
• Primary Completion: 2025-12-06
• Study Completion: 2026-01-06

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Patients with non-restorable mandibular molars
• Both sexes with age range from 20 years to 45 years
• Good oral hygiene
• Adequate alveolar bone dimensions for implant replacement
• Adequate bone volume after extraction to achieve primary stability of the immediate implant
• Co-operative patient

Exclusion Criteria

• Patients with any systemic disease as uncontrolled diabetes or osteoporosis
• Heavy smokers with smokers more than 10 cigarettes per day
• Pregnancy
• Patients with any signs of active infection or pus formation
• Patients undergoing chemotherapy or radiotherapy, immunocompromised patients

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Horizontal bone thickness in millimeters	6 months postoperative	Two CBCT images will be taken, one immediately after surgery (baseline) and the other at 6 months post-surgically

Secondary Outcome Measures

Name	Time	Method
Vertical bone height in millimeters	6 months postoperative	Two CBCT images will be taken, one 2 days after surgery (baseline) and the other at 6 months post-surgically
Pain intensity	One week postoperative	The pain will be recorded by participants at 1, 3, and 7 days after surgery using the Visual Analogue Scale (VAS), which ranges from 0 to 10. The minimum score is 0, indicating no pain, and the maximum score is 10, representing the worst possible pain. Higher scores on the VAS indicate worse outcomes in terms of pain experienced.