Study on Short Chain Fatty Acids Concentration in Breast Milk and Its Correlation With the Maternal Diet
- Conditions
- Short Chain Fatty Acids Concentration in Breast Milk
- Registration Number
- NCT02301728
- Lead Sponsor
- Federico II University
- Brief Summary
The purpose of this study is to determine whether the acetate, butyrate and propionate concentration in breast milk and to evaluate the possible correlation of these concentrations with maternal diet.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
- parturients women at term hospitalized in the Department of Obstetrics, Gynecology and Pathophysiology of Human Reproduction, "Federico II" University of Naples.
Exclusion Criteria
- infections,
- diabetes and other chronic diseases at the level of each organ or system,
- diseases of pregnancy.
- antibiotics, prebiotics, probiotics and synbiotics in the 30 days prior to the first observation.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method butyrate, acetate and propionate concentration 10 days after delivery and every 30 days until the fifth month after delivery
- Secondary Outcome Measures
Name Time Method Relationship between short chain fatty acids in breast milk and maternal diet (amount of fibers in maternal diet and based on this it will evaluate the variations in short chain fatty acids concentration) 10 days after delivery and every 30 days until the fifth month after delivery Relationship between short chain fatty acids in breast milk and maternal diet will be measured by assessing the amount of fibers in maternal diet and based on this it will evaluate the variations in short chain fatty acids concentration. These assessments will be carried out by using a food diary carefully compiled by mothers before each sampling of breast milk
Trial Locations
- Locations (1)
"Federico II" University of Naples
🇮🇹Naples, Italy