NCT02834845已完成4 期
Comparison of Effects of Sevoflurane and Desflurane on Cerebral Oxygenation During Controlled Hypotension
Ufuk University1 个研究点 分布在 1 个国家目标入组 95 人开始时间: 2016年6月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 95
- 试验地点
- 1
- 主要终点
- Cerebral oxygen saturation as measured by Near Infrared Spectroscopy
研究概览
简要总结
Controlled hypotension is a preferred method for reducing surgical bleeding during septoplasty operations however, the level of hypotension and bradycardia should not disrupt cerebral oxygenation. On this account, the investigators aim to investigate the effects of different volatile anesthetics combined with a short-acting opioid on cerebral oxygenation during controlled hypotension using near infrared spectroscopy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients in American Society of Anesthesiology (ASA) classification I and II
- •Patients undergoing elective septoplasty operation
排除标准
- •Patients in ASA classification III and higher
- •Emergency surgery
- •Patients in New York Heart Association classification III-IV
- •Patients with known allergy to drugs used in the study
研究组 & 干预措施
Sevoflurane
Experimental
干预措施: Sevoflurane (Drug)
Desflurane
Experimental
干预措施: Desflurane (Drug)
结局指标
主要结局
Cerebral oxygen saturation as measured by Near Infrared Spectroscopy
时间窗: Duration of surgery
The effect of sevoflurane and desflurane on NIRS values
次要结局
- The effect of anesthetics on hemodynamic variables(Duration of surgery)
- Total remifentanil consumption as measured in micrograms(Duration of surgery)
研究者
Perihan Ekmekçi
Associate Professor
Ufuk University
研究点 (1)
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