Comparison between sedating effect of Midazolam and Dexmedetomidine in intubated poisoned patients
Phase 3
Recruiting
- Conditions
- Sedation before Intubation.
- Registration Number
- IRCT20211022052838N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patients with American society of anesthesiologist (ASA) class 3 and 4 who are admitted in ICU of poisoned patients
Age between 18 to 80
Patients whom are going to be intubated
Not taking sedative drugs before admitting to intensive care unit (ICU)
Exclusion Criteria
known allergy to any of the drugs used in this study
advanced liver disease
Serum creatinine level above 200 micromol/liter
Unstable angina or acute myocardial infarction patients
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of sedation caused by drug according to RASS scale. Timepoint: Before intervention and then every 2 hours. Method of measurement: RASS scale system is a known scale in the world that measured the rate of sedation whom admitted to ICU. Scoring points in this scale include -5 to +4 that the +4 point belongs to agitated and aggressive patients who are a threat for ICU personals. the -5 points belongs to the patients who are not responding to voice and physical stimulations and they are not conscious. the rest of points are spectrum between these two scores.;Blood pressure in the admitted patients of ICU. Timepoint: Before intervention and then every 2 hours. Method of measurement: Vital sign monitoring device.;Heart rate. Timepoint: Before intervention and then every 2 hours. Method of measurement: Vital sign monitoring device.
- Secondary Outcome Measures
Name Time Method