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临床试验/NCT01133964
NCT01133964已完成不适用

Dairy Proteins and Postprandial Appetite Regulation and Energy Expenditure

University of Copenhagen2 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2008年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
22
试验地点
2
主要终点
Subjective appetite sensation

研究概览

简要总结

The aim of this study is to examine the effect of dairy proteins (whey and casein) on postprandial appetite regulation and energy expenditure.

详细描述

Several studies have shown that a high protein intake is associated with a increased loss of body weight and body fat as compared to a diet with a normal or low protein content. The effect seems to be due to a higher diet induced thermogenesis and increase satiety.

Milk has a high content of proteins. It contains two very different types of protein: whey and casein. Whey is a soluble protein whereas casein clots into the stomach, which delays its gastric emptying and thus probably results in a slower release of amino acids. It is therefore very likely that the two types of protein affect the thermogenesis and appetite regulation differently.

The aim of the present study is to examine the effect of dairy proteins (whey and casein) on postprandial energy expenditure, substrate oxidation and appetite regulation.

The study will have a cross-over design including four meals each including a test drink (milk, casein drink, whey drink or water).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Single (Investigator)

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • healthy males
  • body mass index (BMI) 25-30 kg/m2
  • 18-50 years
  • weight stable

排除标准

  • regular use of medicine
  • elitist athletes
  • participation in other intervention studies

结局指标

主要结局

Subjective appetite sensation

时间窗: 5 hours

Energy expenditure

时间窗: 5 hours

Substrate oxidation

时间窗: 5 hours

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (2)

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