Dairy Proteins and Postprandial Appetite Regulation and Energy Expenditure
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Copenhagen
- Enrollment
- 22
- Locations
- 1
- Primary Endpoint
- Subjective appetite sensation
Overview
Brief Summary
The aim of this study is to examine the effect of dairy proteins (whey and casein) on postprandial appetite regulation and energy expenditure.
Detailed Description
Several studies have shown that a high protein intake is associated with a increased loss of body weight and body fat as compared to a diet with a normal or low protein content. The effect seems to be due to a higher diet induced thermogenesis and increase satiety.
Milk has a high content of proteins. It contains two very different types of protein: whey and casein. Whey is a soluble protein whereas casein clots into the stomach, which delays its gastric emptying and thus probably results in a slower release of amino acids. It is therefore very likely that the two types of protein affect the thermogenesis and appetite regulation differently.
The aim of the present study is to examine the effect of dairy proteins (whey and casein) on postprandial energy expenditure, substrate oxidation and appetite regulation.
The study will have a cross-over design including four meals each including a test drink (milk, casein drink, whey drink or water).
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Prevention
- Masking
- Single (Investigator)
Eligibility Criteria
- Ages
- 18 Years to 50 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •healthy males
- •body mass index (BMI) 25-30 kg/m2
- •18-50 years
- •weight stable
Exclusion Criteria
- •regular use of medicine
- •elitist athletes
- •participation in other intervention studies
Outcomes
Primary Outcomes
Subjective appetite sensation
Time Frame: 5 hours
Energy expenditure
Time Frame: 5 hours
Substrate oxidation
Time Frame: 5 hours
Secondary Outcomes
No secondary outcomes reported