To compare Effectiveness of two drugs Esmolol and Lignocaine for decreasing the Pressor Response during artificial tube insertion in respiratory tube under General Anaesthesia
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/12/048275
- Lead Sponsor
- Department of Anaesthesiology SMS MEDICAL COLLEGE AND HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of either sex scheduled to undergo elective surgical procedures under general anesthesia and endotracheal intubation.
Age 20 years to 50 years
Weight 50 kg to 80 kg
Patients of ASA grade 1 and 2.
Patient willing to give the consent.
Exclusion Criteria
Patients with history of known allergic to study drugs.History of consumption of antihypertensive drugs, sedatives, Hypnotics and antidepressants preoperatively.Pre-existing cardiovascular disease, significant respiratory, renal and hepatic disorder.History of drugs or alcohol abuse.
Pregnant patients
Patients requiring rapid sequence induction of anaesthesia
Anticipated difficult intubation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the difference in changes in haemodynamic responses (heart rate, SBP, DBP, MAP) from baseline to different time interval in the two groups.Timepoint: 0, 1,2,3,4,5,10,15 min after intubation
- Secondary Outcome Measures
Name Time Method To determine the difference in percentage in cases who develop side effect in both group.Timepoint: upto 24 hours of extubation