A comparative study between two different doses of buprenorphine as an adjuvant to 0.5% levobupivacaine in ultrasound guided supraclavicular brachial plexus block.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- 1)Heart rate
研究概览
简要总结
usg guided brachial plexus block is one of the most popular peripheral nerve block techniques has become forst choice of anaesthesia for upper extremity surgery as it is minimally alert systemic physiology . ultrasound imaging allow direct visulisation of peripheral nerve s, the block needle tip and the local anaesthetic distribution.levobupivacaine ,the pure enantiomer of bupivacaine ,has less cardiac and central nervous system toxicity compared to bupivacaine .buprenorphine is u -receptor partial agonist oipiod similar in structure to morphinebut 33 time more potent than morphine .this study compare the effect of two different doses of BUPRENORPHINE as an aduvant added to 0.5% levobupivacaine . in our study we are using usg guide techniques of supraclavicula brachial plexus block
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •patient of asa physical grade 2 18 to 65 year age both sexes posted for elective surgeries of upper limb.
排除标准
- •history of infection at the site of block coagulopathies patient with known hypersensitivity to lacal anaesthetics pregnant women preexisting coagulopathies neck deformities.
结局指标
主要结局
1)Heart rate
时间窗: 1)Time at which procedure of giving block is | finished. | 2)Five minute | 3)Ten minute | 3)Fifteen minute | 4)Twenty minute | 5)Fourty minute
2)Mean arterial pressure
时间窗: 1)Time at which procedure of giving block is | finished. | 2)Five minute | 3)Ten minute | 3)Fifteen minute | 4)Twenty minute | 5)Fourty minute
3)Saturation
时间窗: 1)Time at which procedure of giving block is | finished. | 2)Five minute | 3)Ten minute | 3)Fifteen minute | 4)Twenty minute | 5)Fourty minute
次要结局
- 1.Heart rate(2.Mean arterial pressure)
研究者
Dr Kaushalya Prakashrao Shinde
Mgm Medical college