3D gaze stability as a meausure for visual-vestibular functio

• Conditions: Cerebellopontine angle tumor; vestibular schwannoma; 10022396; 10047518

• Registration Number: NL-OMON56520
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

- Normal hearing in the unaffected ear
- Fuctional vision in both eyes
- Informed concent (toestemmingsformulier).
- Solitary vestibular schwannoma
- Stationairy retinal dysfunction syndrom

Exclusion Criteria

- neurological or psychiatric disease
- dizziness due to side effect medication
- Alcohol or drug abuse up to 6 months previously
- HIV
- Hepatitis B
- History of *closed head injury*,
- Pregnancy

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary:<br /><br>• Retinal slip velocity in °/s, the movement of the eye relative to the image.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary:<br /><br>• Saccade and smooth pursuit amplitude and latency as a reference for the<br /><br>accuracy of oculomotor response when viewing a moving image with a stationary<br /><br>head.<br /><br>• Hearing threshold in dB as a reference for the integrity of the<br /><br>audiovestibular end organ.<br /><br>• Speech discrimination in % as a reference for the integrity of the<br /><br>audiovestibular end organ.<br /><br>• Visual acuity in % as a reference for the integrity of the input from the<br /><br>visual system.<br /><br>• DHI score, ERGO score, and VAS score for documentation of the experience of<br /><br>balance complaints.</p><br>