The Impact of Comprehensive Medication Management Services on Clinical Outcomes in Patients With Cardiovascular Diseases at Primary Care Level
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 133
- 试验地点
- 2
- 主要终点
- The impact of CMM services on blood pressure in elderly patients with established CVD
研究概览
简要总结
Patients with established cardiovascular disease (CVD) often have multiple medications that increase the risk of prevalence of drug therapy problems (DTP), subsequently leading to unfavourable clinical and health outcomes. By providing Comprehensive Medication Management (CMM) services to patients within a healthcare system, pharmacists assess patients' medication-related needs, identify and prevent DTP, develop individualized care plan for each individual patient and evaluate and monitor outcomes. Thus, the CMM services delivered at the primary care level in collaboration with general practitioners and other healthcare providers could address this problem and by optimizing therapy improve patients' clinical outcomes and quality of life. Studies have shown that patients with chronic diseases have the greatest benefit from the CMM services. The aim of this study is to evaluate the impact of CMM services on clinical and humanistic outcomes in patients with established CVD. The study will employ prospective, longitudinal, pre- and postintervention study with a 1-year patient follow-up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 80 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hypertension
- •Established cardiovascular disease
排除标准
- •Organic, including symptomatic, mental disorders
- •Mental and behavioural disorders due to psychoactive substance use
- •Schizophrenia, schizotypal and delusional disorders
- •Behavioural syndromes associated with physiological disturbances and physical factors
- •Disorders of adult personality and behaviour
- •Mental retardation
- •Disorders of psychological development
研究组 & 干预措施
Intervention group
In addition to usual care provided by general practitioner (GP) and other health care providers, a pharmacist-practitioner in collaboration with GPs from the study setting provided CMM services to patients in the intervention group. Based on the pre-defined inclusion criteria, GPs were selecting patients and referring them to the pharmacist. The individual consultation with the patient was held at the private counselling area where pharmacist and patient were able to talk face-to-face apart from the other patients. The initial assessment lasted 60-90 minutes and the follow-up evaluations 30-60 minutes. Alternatively, patients were followed-up by telephone. Communication with GPs took place in a written (electronic consultation system Health net. PRO; e-mail) and, if needed by face-to-face conversation. Each patient in the intervention group needed to agree to participate in the study by signing an Informed consent form.
干预措施: Comprehensive Medication Management services (Other)
Control group
Patients in the control group received the usual care which includes GP and other health care provider visits. Data for the patients pertaining to the control group were provided by the 'control' GP and collected parallel with the intervention group. 'Control' GP profile corresponded to the profile of GPs included in the intervention group - the number of years of professional experience in the primary health care less than ten.
结局指标
主要结局
The impact of CMM services on blood pressure in elderly patients with established CVD
时间窗: 1 year
Within- and between-treatment differences for the intervention and the control group in blood pressure.
次要结局
- The impact of CMM services on drug therapy problems in elderly patients with established CVD(1 year)
- The impact of CMM services on LDL cholesterol, triglycerides, HDL cholesterol and total cholesterol in elderly patients with established CVD(1 year)
- The impact of CMM services on health care utilization in elderly patients with established CVD(1 year)
- The impact of CMM services on health related quality of life in elderly patients with established CVD assessed by EQ-5D-5L instrument.(1 year)
- The impact of CMM services on glycated haemoglobin in elderly patients with established CVD(1 year)
研究者
Iva Mucalo
Associate Professor
University of Zagreb