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临床试验/NCT04778891
NCT04778891已完成不适用

The Impact of Comprehensive Medication Management Services on Clinical Outcomes in Patients With Cardiovascular Diseases at Primary Care Level

University of Zagreb4 个研究点 分布在 1 个国家目标入组 133 人开始时间: 2018年1月8日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
133
试验地点
4
主要终点
The impact of CMM services on blood pressure in elderly patients with established CVD

研究概览

简要总结

Patients with established cardiovascular disease (CVD) often have multiple medications that increase the risk of prevalence of drug therapy problems (DTP), subsequently leading to unfavourable clinical and health outcomes. By providing Comprehensive Medication Management (CMM) services to patients within a healthcare system, pharmacists assess patients' medication-related needs, identify and prevent DTP, develop individualized care plan for each individual patient and evaluate and monitor outcomes. Thus, the CMM services delivered at the primary care level in collaboration with general practitioners and other healthcare providers could address this problem and by optimizing therapy improve patients' clinical outcomes and quality of life. Studies have shown that patients with chronic diseases have the greatest benefit from the CMM services. The aim of this study is to evaluate the impact of CMM services on clinical and humanistic outcomes in patients with established CVD. The study will employ prospective, longitudinal, pre- and postintervention study with a 1-year patient follow-up.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
65 Years 至 80 Years(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Hypertension
  • Established cardiovascular disease

排除标准

  • Organic, including symptomatic, mental disorders
  • Mental and behavioural disorders due to psychoactive substance use
  • Schizophrenia, schizotypal and delusional disorders
  • Behavioural syndromes associated with physiological disturbances and physical factors
  • Disorders of adult personality and behaviour
  • Mental retardation
  • Disorders of psychological development

结局指标

主要结局

The impact of CMM services on blood pressure in elderly patients with established CVD

时间窗: 1 year

Within- and between-treatment differences for the intervention and the control group in blood pressure.

次要结局

  • The impact of CMM services on drug therapy problems in elderly patients with established CVD(1 year)
  • The impact of CMM services on LDL cholesterol, triglycerides, HDL cholesterol and total cholesterol in elderly patients with established CVD(1 year)
  • The impact of CMM services on health care utilization in elderly patients with established CVD(1 year)
  • The impact of CMM services on health related quality of life in elderly patients with established CVD assessed by EQ-5D-5L instrument.(1 year)
  • The impact of CMM services on glycated haemoglobin in elderly patients with established CVD(1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Iva Mucalo

Associate Professor

University of Zagreb

研究点 (4)

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