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Clinical Trials/NCT04778891
NCT04778891
Completed
Not Applicable

The Impact of Comprehensive Medication Management Services on Clinical Outcomes in Patients With Cardiovascular Diseases at Primary Care Level

University of Zagreb2 sites in 1 country133 target enrollmentJanuary 8, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiovascular Diseases in Old Age
Sponsor
University of Zagreb
Enrollment
133
Locations
2
Primary Endpoint
The impact of CMM services on blood pressure in elderly patients with established CVD
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

Patients with established cardiovascular disease (CVD) often have multiple medications that increase the risk of prevalence of drug therapy problems (DTP), subsequently leading to unfavourable clinical and health outcomes. By providing Comprehensive Medication Management (CMM) services to patients within a healthcare system, pharmacists assess patients' medication-related needs, identify and prevent DTP, develop individualized care plan for each individual patient and evaluate and monitor outcomes. Thus, the CMM services delivered at the primary care level in collaboration with general practitioners and other healthcare providers could address this problem and by optimizing therapy improve patients' clinical outcomes and quality of life. Studies have shown that patients with chronic diseases have the greatest benefit from the CMM services. The aim of this study is to evaluate the impact of CMM services on clinical and humanistic outcomes in patients with established CVD. The study will employ prospective, longitudinal, pre- and postintervention study with a 1-year patient follow-up.

Registry
clinicaltrials.gov
Start Date
January 8, 2018
End Date
January 17, 2021
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Iva Mucalo

Associate Professor

University of Zagreb

Eligibility Criteria

Inclusion Criteria

  • Hypertension
  • Established cardiovascular disease

Exclusion Criteria

  • Organic, including symptomatic, mental disorders
  • Mental and behavioural disorders due to psychoactive substance use
  • Schizophrenia, schizotypal and delusional disorders
  • Behavioural syndromes associated with physiological disturbances and physical factors
  • Disorders of adult personality and behaviour
  • Mental retardation
  • Disorders of psychological development

Outcomes

Primary Outcomes

The impact of CMM services on blood pressure in elderly patients with established CVD

Time Frame: 1 year

Within- and between-treatment differences for the intervention and the control group in blood pressure.

Secondary Outcomes

  • The impact of CMM services on drug therapy problems in elderly patients with established CVD(1 year)
  • The impact of CMM services on LDL cholesterol, triglycerides, HDL cholesterol and total cholesterol in elderly patients with established CVD(1 year)
  • The impact of CMM services on health care utilization in elderly patients with established CVD(1 year)
  • The impact of CMM services on health related quality of life in elderly patients with established CVD assessed by EQ-5D-5L instrument.(1 year)
  • The impact of CMM services on glycated haemoglobin in elderly patients with established CVD(1 year)

Study Sites (2)

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