Study for protein expression of the complement activation product C4a in patient plasma of non-small cell lung cancer of different clinical stages

Not Applicable

Recruiting

• Conditions: non-small cell lung cancer

• Registration Number: ITMCTR1900002409
• Lead Sponsor: Yueyang Hospital of Integrated Traditional Chinese and Western Medicine affiliated to Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1 Inclusion criteria of patients with non-small cell lung cancer:
(1) Participants who are dignosed as stage I or IV non-small cell lung cancer by pathological or cytological methods;
(2) Aged 30~80;
(3) ECOG score: 0-3, KPS=50;
(4) Participants have signed informed consent and have good compliance.
2. Inclusion criteria of non-cancer controls:
(1) Participants who are not diagnosed as cancer;
(2) Aged 30~80 years;
(3) Participants have signed informed consent.

Exclusion Criteria

1. Exclusion criteria of patients with non-small cell lung cancer:
(1) Participants who have received immunoenhancer or immunosuppressant half a month before sampling;
(2) Participants who have received radiotherapy and chemotherapy half a month before sampling;
(3) Participants who are diagnosed as severe recurrent diseases (such as autoimmune diseases and leukemia);
(4) Participants who are diagnosed as microbial (including bacterial, viral and mycoplasma infection) infection;
(5) Participants who have received blood transfusion one year before sampling.
2. Exclusion criteria of non-cancer controls:
(1) Participants who are diagnosed as severe recurrent diseases (such as autoimmune diseases and leukemia);
(2) Participants who are diagnosed as microbial (including bacterial, viral and mycoplasma infection) infection;
(3) Participants who received blood transfusion one year before sampling.

Study & Design

• Study Type: Basic Science
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
APTT/PT/TT/FIB;C4a level in plasma;