Dihydroartemisinin–Piperaquine versus Sulfadoxine–Pyrimethamine Use for the Prevention of Malaria during Pregnancy
- Conditions
- Malaria
- Registration Number
- PACTR202002644579177
- Lead Sponsor
- Royal Society of Tropical Medicine and Hygiene
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- Female
- Target Recruitment
- 250
•Pregnant women aged 15-49 years
•Attending antenatal clinic (ANC) for the first time in this current pregnancy
•Gestation of 16-20 weeks (as assessed by LMP and/or ultra-scan)
•HIV-negative pregnant women
•No current history of receiving IPTp-SP
•Willing to provide informed written consent
•Planning to stay in Maiduguri and attending ANC and have child delivery at University of Maiduguri Teaching Hospital, Maiduguri
•A history of allergic reaction to sulfa drugs (SP or cotrimoxazole) or DP
•Having haemoglobin level < 7 g/dl
•Positive test for falciparum malaria
•History of receipt of antimalarials or antibiotics with antimalarial activity (cotrimoxazole, rifampin, doxycycline, clindamycin, tetracycline, erythromycin, azithromycin, chloramphenicol) in the past month
•Women with sickle cell disease
•Women with high-risk pregnancies (presence of high blood pressure and diabetes)
•HIV- Positive women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method