Effect of vibrotactile stimulation on Parkinsons tremor an explorative study

Completed

Conditions: Parkinson
Tremor
10028037

Registration Number: NL-OMON51063

Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 37

Inclusion Criteria

-18-80 years old
-Have a diagnosis of idiopathic PD made by a movement disorders specialist.
-Medically optimized without planned medication changes for the duration of the
study.
-Resting tremor subscore >/<= 2 of the most affected arm on the Movement
Disorders Society Unified Parkinson*s Disease Rating Scale (MDS-UPDRS) item 2.10
-Postural tremor subscore >/<= 1 of the most affected arm on the MDS-UPDRS item
3.15

Exclusion Criteria

-The presence of additional neurologic diseases that might confound testing or
the coexistence of PD and essential tremor together (action tremor that was
present prior to the development of parkinsonism).
-Moderate to severe peripheral neuropathy (reduced vibratory sensation)
-Montreal cognitive assessment (MoCA) score < 20 or previously documented
dementia
-Unable to walk without walking aid.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The effect of vibrotactile stimulation at tremor frequency on tremor severity<br /><br>(delta tremor power between stimulation and baseline). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The effect of continuous vibrotactile stimulation, stimulation at 1.5 times<br /><br>tremor frequency and sham on tremor severity (delta tremor power between<br /><br>stimulation/sham and baseline).<br /><br><br /><br>The effect of continuous vibrotactile stimulation on bradykinesia (average<br /><br>button presses per second in the keyboard finger tapping test during<br /><br>stimulation versus sham).<br /><br><br /><br>The effect of vibrotactile stimulation at step frequency on gait, with three<br /><br>outcome measures of Timed up and go performance: Time to complete, number of<br /><br>freezing episodes and duration of freezing episodes. </p><br>