Effect of Wide Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients Undergoing Off-pump Coronary Artery Bypass Graft

Not Applicable

Completed

• Conditions: Stroke Volume Variation
• Interventions: Other: HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading

• Registration Number: NCT01404455
• Lead Sponsor: Severance Hospital

Brief Summary

The investigators examined the predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure undergoing off-pump coronary artery bypass graft

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12
• Study First Submitted: 2011-04-01
• Study First Submitted QC: 2011-07-27
• Study First Posted: 2011-07-28
• Primary Completion: 2011-08
• Study Completion: 2011-08
• Status Verified: 2012-01
• Last Update Submitted: 2012-01-16
• Last Update Posted: 2012-01-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

• 1. Age ≥ 20
• 2. elective off-pump coronary artery bypass graft

Exclusion Criteria

• 1. arrhythmia
• 2.EF <40%
• 3.valvular heart dz
• 4.pul HTN
• 5.PAOD
• 6.lung dz
• 7.NYHA IV
• 8.ESRD

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Normal pulse pressure	HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading	pulse pressure \<60mmHg
Wide pulse pressure	HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading	pulse pressure ≥60mmHg

Primary Outcome Measures

Name	Time	Method
The predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure	30 min

Secondary Outcome Measures

Name	Time	Method
Cut off value of stroke volume variation for predicting fluid responsiveness in patients with wide pulse pressure	30 min

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of