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Clinical Trials/NCT04250272
NCT04250272
Unknown
Not Applicable

Serratus Anterior Plane Block vs. Intercostal Nerve Block for Postoperative Analgesic Effect After Video-assisted Thoracoscopic Lobectomy: A Randomized Prospective Study

Kyungpook National University Hospital1 site in 1 country50 target enrollmentAugust 16, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Analgesia
Sponsor
Kyungpook National University Hospital
Enrollment
50
Locations
1
Primary Endpoint
Postoperative pain: numeric rating scale
Last Updated
6 years ago

Overview

Brief Summary

A prospective randomized controlled study was undertaken to compare the postoperative analgesic effect between ultrasound-guided serratus anterior plane block and intercostal nerve block after video-assisted thoracoscopic lobectomy.

Detailed Description

Post-thoracotomy pain is one of the most notorious postsurgical pains that one can experience. The pain is known to last for an extensive period of time with significantly high intensity. In field of thoracic surgery, video-assisted thoracoscopic surgery has been played an important role in alleviating the postoperative pain. In field of anesthesiology, various attempts to alleviate post-thoracotomy pain have been tried along advancement of thoracic surgical techniques. It began with postoperative medication of non-steroid anti-inflammatory drugs, opioids and progressed into implementations such as local analgesia, thoracic epidural block, paravertebral block, intercostal nerve block, interpleural block and serratus anterior plane block. Many analgesic methods have been applied to alleviate postoperative pain in patients who have undergone thoracoscopic surgeries. However, there are no prospective randomized controlled studies between intercostal nerve block and serratus anterior plane block in video-assisted thoracoscopic lobectomy. The main purpose of this study is to compare and analyze the effects between conventional intercostal nerve block and newly introduced serratus anterior plane block in lung cancer patients who have undergone video-assisted thoracoscopic lobectomy. This prospective study will discover the efficacy and differences between two methods.

Registry
clinicaltrials.gov
Start Date
August 16, 2019
End Date
February 29, 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Saeyoung Kim, MD, PhD

Associate professor

Kyungpook National University Hospital

Eligibility Criteria

Inclusion Criteria

  • lung cancer
  • American Society of Anesthesiologists (ASA) I-III class
  • Video-assisted thoracoscopic lobectomy

Exclusion Criteria

  • previous history of allergy to local anesthetics
  • psychological disorder
  • chronic analgesics or sedatives use
  • coagulopathy
  • The presence of systemic infection or local infection at injection site
  • Pregnancy

Outcomes

Primary Outcomes

Postoperative pain: numeric rating scale

Time Frame: 24 hours later operation

Postoperative pain will be evaluated using a numeric rating scale (0 being no pain, 10 being worst pain imaginable)

Secondary Outcomes

  • Number of analgesics consumption(through study completion, an average of 1 yea)
  • Amount of analgesics consumption(: through study completion, an average of 1 year)

Study Sites (1)

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