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Clinical Trials/NCT03983941
NCT03983941
Terminated
Phase 3

Comparison of Postoperative Analgesic Efficacy of Adductor Canal Block With IPACK Versus Adductor Canal and Popliteal Sciatic Nerve Block in Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction

Sujana Dontukurthy1 site in 1 country7 target enrollmentAugust 30, 2019

Overview

Phase
Phase 3
Intervention
Ropivacaine injection
Conditions
Anterior Cruciate Ligament Tear
Sponsor
Sujana Dontukurthy
Enrollment
7
Locations
1
Primary Endpoint
Average Post-operative Pain Score
Status
Terminated
Last Updated
4 years ago

Overview

Brief Summary

This is a prospective study comparing femoral nerve block plus sciatic nerve block to femoral nerve block plus infiltration of the posterior knee capsule (IPACK) in patients undergoing arthroscopic anterior cruciate ligament reconstruction. Femoral nerve block via the adductor canal (FNB-AC) with IPACK may provide effective analgesia while avoiding the motor block involved with sciatic nerve block. The lack of motor block is important to facilitate postoperative ambulation and physical therapy.

Registry
clinicaltrials.gov
Start Date
August 30, 2019
End Date
November 7, 2019
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Sujana Dontukurthy
Responsible Party
Sponsor Investigator
Principal Investigator

Sujana Dontukurthy

Clinical Assistant Professor of Anesthesiology

Nationwide Children's Hospital

Eligibility Criteria

Inclusion Criteria

  • Patients less than 21 years of age
  • American Society of Anesthesiologists physical status I and II
  • Undergoing elective anterior cruciate ligament reconstruction

Exclusion Criteria

  • They are unable or unwilling to take part in the study
  • History of allergy to any of the medications administered for the nerve block
  • Contraindication to peripheral nerve block
  • Patients who are unable to understand instructions or questions related to the study or the families required language interpretation
  • Patients who consume opioid medications for more than three days per week for more than a month prior to surgery

Arms & Interventions

FNB-AC + Sciatic nerve block

Patients will receive up to 20 mL of 0.2% ropivacaine for FNB-AC and up to 20 mL of 0.2% ropivacaine for sciatic nerve block under ultrasound guidance.

Intervention: Ropivacaine injection

FNB-AC + IPACK

Patients will receive up to 20 mL of 0.2% ropivacaine for FNB-AC and up to 20 mL of 0.2% ropivacaine for posterior knee capsular infiltration under ultrasound guidance (IPACK)

Intervention: Ropivacaine injection

Outcomes

Primary Outcomes

Average Post-operative Pain Score

Time Frame: Immediately post-operatively and up to 48 hours post-discharge, an average of 48 hours

Visual Analogue Scale (VAS) pain scores (0 being no pain and 10 being worst pain) from arrival to post-anesthesia care unit (PACU) to 48 hours after discharge from surgery center.

Secondary Outcomes

  • Number of Opioid Doses Administered(Intra-operative and up to 48 hours post-discharge, an average of 48 hours)

Study Sites (1)

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