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Clinical Trials/NCT03395990
NCT03395990
Completed
Not Applicable

Evaluation of the Comparative Analgesic Value of Adductor Canal Block Versus Femoral Block Following Total Knee Arthroplasty

Duke University1 site in 1 country16 target enrollmentMarch 27, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Osteo Arthritis Knee
Sponsor
Duke University
Enrollment
16
Locations
1
Primary Endpoint
Pain Intensity as Measured by 11-point Verbal Numeric Rating Scale (NRS-11) for Pain.
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

An observational study of the effect of femoral nerve block in addition to an adductor canal block for pain following total knee arthroplasty.

Detailed Description

Subjects undergoing total knee arthroplasty will receive a preoperative adductor canal block with continuous catheter. Following a standardized general anesthetic for the procedure, subjects will be asked to rate their pain using the NRS-11 pain scale in the recovery room. Once the pain is reported at a 5/10 or above, a femoral nerve block will be performed using either 2% chloroprocaine or saline placebo (randomized). Pain scores are then evaluated over the next 30 minutes by a blinded investigator to determine if the femoral block adds any additional analgesic benefit over an adductor canal block.

Registry
clinicaltrials.gov
Start Date
March 27, 2016
End Date
October 19, 2016
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients scheduled for elective total knee arthroplasty
  • ASA Physical Status I-III
  • BMI 18-40 kg/m2

Exclusion Criteria

  • Inability to cooperate with protocol
  • Inability to understand or speak English
  • Allergy to any local anesthetic
  • Chronic opioid consumption/abuse (30 or more morphine mg equivalents/day)
  • Contraindication to adductor canal or femoral nerve block

Outcomes

Primary Outcomes

Pain Intensity as Measured by 11-point Verbal Numeric Rating Scale (NRS-11) for Pain.

Time Frame: Baseline, up to 30 minutes.

Pain intensity prior to intervention and at 5 minute intervals after intervention. The 11-point Numeric Rating Scale quantifies a subject's pain experience from 0/10 (no pain) to 10/10 (worst pain imaginable).

Study Sites (1)

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