Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty

Not Applicable

Completed

• Conditions: Osteo Arthritis Knee

• Registration Number: NCT03395990
• Lead Sponsor: Duke University

Brief Summary

An observational study of the effect of femoral nerve block in addition to an adductor canal block for pain following total knee arthroplasty.

Detailed Description

Subjects undergoing total knee arthroplasty will receive a preoperative adductor canal block with continuous catheter. Following a standardized general anesthetic for the procedure, subjects will be asked to rate their pain using the NRS-11 pain scale in the recovery room. Once the pain is reported at a 5/10 or above, a femoral nerve block will be performed using either 2% chloroprocaine or saline placebo (randomized). Pain scores are then evaluated over the next 30 minutes by a blinded investigator to determine if the femoral block adds any additional analgesic benefit over an adductor canal block.

Study Timeline

• Study Start: 2016-03-27
• Primary Completion: 2016-10-19
• Study Completion: 2016-10-19
• Study First Submitted: 2017-12-18
• Study First Submitted QC: 2018-01-04
• Study First Posted: 2018-01-10
• Status Verified: 2020-06
• Results First Submitted: 2020-06-02
• Results First Submitted QC: 2020-06-02
• Last Update Submitted: 2020-06-02
• Results First Posted: 2020-06-17
• Last Update Posted: 2020-06-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Patients scheduled for elective total knee arthroplasty
• ASA Physical Status I-III
• BMI 18-40 kg/m2

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Exclusion Criteria

• Inability to cooperate with protocol
• Inability to understand or speak English
• Allergy to any local anesthetic
• Chronic opioid consumption/abuse (30 or more morphine mg equivalents/day)
• Contraindication to adductor canal or femoral nerve block

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Pain Intensity as Measured by 11-point Verbal Numeric Rating Scale (NRS-11) for Pain.	Baseline, up to 30 minutes.	Pain intensity prior to intervention and at 5 minute intervals after intervention. The 11-point Numeric Rating Scale quantifies a subject's pain experience from 0/10 (no pain) to 10/10 (worst pain imaginable).

Trial Locations

Locations (1)

Duke University Hospital; 🇺🇸 Durham, North Carolina, United States