MedPath

A Study to Evaluate the Efficacy and Safety of 2.5mg and 5mg Tadalafil Given Once a Day to Men With Erectile Dysfunction

Phase 3
Completed
Conditions
Erectile Dysfunction
Interventions
Drug: placebo
Registration Number
NCT00381732
Lead Sponsor
Eli Lilly and Company
Brief Summary

This is a multicenter, randomized, double blind, placebo-controlled, parallel design study to evaluate the efficacy and safety of 2.5mg and 5mg tadalafil taken once daily in men with erectile dysfunction.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
280
Inclusion Criteria
  • Men with erectile dysfunction
  • At least 18 years of age
Exclusion Criteria
  • Certain chronic medical conditions including cardiac disease, congestive heart failure, kidney or liver disease, cancer and HIV
  • A history of certain impotence disorders
  • History of specified pelvic surgery
  • Any significant genital abnormality identified at the start of the study

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1placeboplacebo tablet
3tadalafil5 mg tadalafil tablet
2tadalafil2.5 mg tadalafil tablet
Primary Outcome Measures
NameTimeMethod
Changes in erectile function measured at baseline and after 6 months of treatment with 2.5mg and 5mg tadalafil; assessment of safety after 1 and 2 years of therapy with 5mg tadalafil.24-128 weeks
Secondary Outcome Measures
NameTimeMethod
Changes in additional aspects of erectile function after 3 and 6 months of treatment; assessment of the pharmacokinetics of tadalafil 2.5mg and 5mg.24 weeks

Trial Locations

Locations (1)

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

🇺🇸

Bothell, Washington, United States

© Copyright 2025. All Rights Reserved by MedPath