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Dexamethasone for cancer-related fatigue in advanced cancer patients - multi-center phase II trial

Phase 2
Conditions
A diagnosis of advanced cancer (defined as metastatic or recurrent)
Fatigue, Cancer, Dexamethasone
none
Registration Number
JPRN-jRCTs031180068
Lead Sponsor
Miura Tomofumi
Brief Summary

The efficacy and safety were evaluated by phase II clinical trial for advanced cancer patients receiving only palliative care and with moderate fatigue. The efficacy and safety were found. However, the efficacy did not achieve the preset outcomes.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
32
Inclusion Criteria

A diagnosis of advanced cancer (defined as metastatic or recurrent) with fatigue score 4 and more using NRS(0-10)
20 years and older
Prognosis over 30 days
No anti-cancer treatment plan
Inpatient receiving palliative care
Performance status 1-3
Conprehension of Japanese
Provided written informed consent

Exclusion Criteria

Patients received corticosteroid therapies within 1 week
Patients received surgery within 4 week
Patients received radiation therapy within 2 week
Patients received anti-tumor treatment within 2 week
Patients had diabetes mellitus, active infection and cognitive disorder

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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