Physiological and Appetitive Effects of Four Weeks of 60 mg/Day CBD Supplementation in an Adult Population
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Energy Intake
研究概览
简要总结
CBD may affect metabolic control and energy intake. However, there is currently little data regarding these specific outcomes in humans. Therefore, this study will investigate whether four weeks of supplementation with 60 mg/day CBD affects energy intake at a single meal, and or fasting blood-based markers of appetite regulation and metabolic health. Healthy, adult volunteers will be assigned to placebo or CBD supplementation, in a randomized controlled trial, comparing changes in outcomes across the supplementation period between groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
盲法说明
Double-blind
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Males and females, aged 18-50, who do not meet the exclusion criteria
排除标准
- 未提供
研究组 & 干预措施
CBD
1 mL hemp oil containing 60 mg/mL CBD, daily.
干预措施: Cannabidiol (CBD) supplementation (Dietary Supplement)
Placebo
1 mL hemp oil containing 0 mg/mL CBD, daily.
干预措施: Placebo supplementation (Dietary Supplement)
结局指标
主要结局
Energy Intake
时间窗: Baseline and after 4 weeks supplementation
Self-selected energy intake at an ad libitum mixed meal
次要结局
- Lipoproteins(Baseline and after 4 weeks supplementation)
- Insulin(Baseline and after 4 weeks supplementation)
- Glucose(Baseline and after 4 weeks supplementation)
- Triglycerides(Baseline and after 4 weeks supplementation)
- CBD(Baseline and after 4 weeks supplementation)
- Liver transaminases(Baseline and after 4 weeks supplementation)
- Hormones implicated in appetite regulation(Baseline and after 4 weeks supplementation)
- Subjective appetite (hunger, fullness, desire to eat)(Baseline and after 4 weeks supplementation)
- self-reported adverse events(During 4 weeks supplementation)
研究者
Lewis James
Senior Lecturer in Nutrition
Loughborough University