EVLP to Evaluate the Eligibility for Transplantation of DCD-Lungs
- Conditions
- Disorders Related to Lung TransplantationGraft Failure
- Interventions
- Procedure: EVLP-DCD Group
- Registration Number
- NCT02061462
- Lead Sponsor
- Policlinico Hospital
- Brief Summary
The procurement of organs from donors after cardiocirculatory death (DCD) is an accepted strategy to increase organ supply.
- Detailed Description
Aim of the investigation: to compare the clinical outcome after transplantation of subjects receiving lungs procured from donors after cardiocirculatory death reconditioned and assessed by EVLP, with that of subjects receiving lungs procured from brain death donors.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 10
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description EVLP-DCD Group EVLP-DCD Group Recipients of lungs procured from DCD donors, reconditioned/evaluated by EVLP
- Primary Outcome Measures
Name Time Method 30 Day Mortality and Graft Survival 30 days 30 day mortality and graft survival is used as a standard research measure to evaluate post transplant outcome
- Secondary Outcome Measures
Name Time Method Duration of mechanical ventilation after transplantation 30 days ICU length of stay after transplantation 30 days Primary Graft Dysfunction 72 hours After Transplantation 72 hours Primary Graft Dysfunction 72 hours after transplantation definition: grade 3 according to the International Society of Heart and Lung Transplantation classification
Trial Locations
- Locations (1)
Fondazione IRCCS a' Granda - Ospedale Maggiore Policlinico
🇮🇹Milan, Italy