Tetanus-diphtheria(Td) vaccine effect on recurrent minor oral aphthous.
Not Applicable
- Conditions
- Recurrent Aphthous stomatitis( minor).Recurrent oral aphthae
- Registration Number
- IRCT201501213989N1
- Lead Sponsor
- Vice chancellor for research,Ardabil University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
20 to 60 years old patients; who have 1 to 3 minor(1-8 millimeters) oral aphthous; with at least one relapse per month,
Exclusion criteria :establishment of anemia; HIV or Behcet's
syndrome ; recipients of tetanus-diphtheria(Td) vaccine in the last five years
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Aphthous remission after treatment. Timepoint: At the beginning and end of the study. Method of measurement: Based on the judgment of those who have studied .Complete remission, partial remission, non-recovery.;The interval between the occurrence of aphthous. Timepoint: 180 days. Method of measurement: One day(24 hours).;The number of aphthous in each recurrence. Timepoint: 180 days. Method of measurement: The number of aphthous.;Measuring pain intensity. Timepoint: 180 days. Method of measurement: A score of 0 to ten according to one's own judgment.;Size of aphthous. Timepoint: 180 days. Method of measurement: milimeter.
- Secondary Outcome Measures
Name Time Method Injection site reactions. Timepoint: Fifteen days after injection. Method of measurement: Physical examination in case of complications.