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Comparison of the effect of doxycycline with Omega-3 fatty acid and low-dose Aspirin on gingival crevicular fluid levels of matrix metalloproteinase-8

Not Applicable
Conditions
Chronic Periodontitis.
Chronic periodontitis
Registration Number
IRCT2013052311771N6
Lead Sponsor
Islamic Azad University Khorasgan Branch (Isfahan)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
45
Inclusion Criteria

chronic mild to moderate periodontitis.
Exclusion criteria: Patients with any infectious or systemic diseases; no drug usage at all; pregnant, breast feeder patients; patients allergic to antibiotics; no scaling and root planning or periodontal surgeries in the last six months; no usage of antibiotic drugs during the last six months; Smokers, alcoholics; patients with poor oral hygiene or patients with poor compliance

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
MMP-8 concentrate in GCF. Timepoint: 0 and 6 weeks. Method of measurement: Nanogram per milliliter by means of ElLISAreader.
Secondary Outcome Measures
NameTimeMethod
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