Exploring the natural history of myopic maculopathy and optic neuropathy in high myopia: Zhongshan High Myopia Cohort

Not Applicable

• Conditions: Individuals with high myopia; Eye Diseases

• Registration Number: ISRCTN56368396
• Lead Sponsor: ational Sun Yat-sen University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-03-12
• Last Update Posted: 25 March 2024
• Study Completion: 2030-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

1. Sphere = -6.00 diopter (cylinder is not included) in both eyes
2. Aged between 7 and 70 years old

Exclusion Criteria

1. Secondary myopia, such as a history of retinopathy of prematurity or neonatal problems, or syndromic myopia with a known genetic disease or connective tissue disorders, such as Stickler or Marfan syndrome
2. History of laser treatment for myopia correction or any intraocular surgery affecting refractive status
3. Have autoimmunity disease such as systemic lupus erythematosus, rheumatoid arthritis;
4. Have severe health problems precluding follow-up such as end-stage heart disease, kidney disease, lung disease, or terminal cancer
5. Have significant ocular media opacity preventing fundus examinations (e.g.dense corneal opacity)
6. Unable to give their own informed consent
7. Plan to move from the area within the next 8 years

Study & Design

• Study Type: Observational
• Study Design: Not specified