Myopic Optic Neuropathy in Chinese High Myopia Population
- Conditions
- Eye Diseases
- Registration Number
- NCT04302220
- Lead Sponsor
- Sun Yat-sen University
- Brief Summary
This study intends to establish a registry cohort to enroll patients with high myopia to study the natural course of myopic optic neuropathy in Chinese adult population.
- Detailed Description
Global prevalence of high myopia brings about markedly increasing of blinding complications as myopic optic neuropathy (MON) and glaucoma. It was estimated that there were 163 million people who have high myopia in 2000, and the population with high myopia would increase to almost one billion (9.8% of the world population) worldwide by 2050.
Glaucoma is the leading cause of irreversible blindness worldwide while it is difficult to distinguish glaucoma among MON in high myopia eyes. However, there lack longitudinal study to illustrate the natural course interpreting the distribution and natural history of MON.
In view of the above problems, this is a longitudinal registry cohort study to observe the long-term changes of structural and functional parameters of MON in high myopia, and to investigate the natural course and associted risk factors that influence the progression in a Chinese adult population.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 813
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Progression of glaucoma within 36 months 3 years Structural and functional changes of glaucoma using visual field, stereoscopic fundus photography.
- Secondary Outcome Measures
Name Time Method Progression of myopia and other structural changes of retina and choroid. 3 years Structural and functional changes of myopia based on axial length and refractive error.
Trial Locations
- Locations (1)
Zhongshan Ophthalmic Center
🇨🇳Guangzhou, Guangdong, China