EUCTR2015-001835-20-BE进行中（未招募）1 期
Morphine intravenous vs. paracetamol intravenous after cardiac surgery in neonates and infants. - Morphine IV vs paracetamol IV for analgosedation in neonates and infants after cardiac surgery
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- Erasmus MC
- 入组人数
- 208
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Informed consent,
- •Neonate / infant aged 0-36 months,
- •Cardiac surgery with the use of CPB.
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range: 208
- •F.1.2 Adults (18-64 years) no
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •No informed consent
- •Known allergy to or intolerance for paracetamol or morphine,
- •Administration of opioids in the 24 hours prior to surgery.
- •Hepatic dysfunction defined as three times the reference value of ALAT/ASAT.
- •Renal insufficiency defined as Pediatric RIFLE category - injury, defined as estimated creatinine clearance reduced by 50% and urine output <0.5 ml/kg/h for 16 hours.
研究者
相似试验
进行中（未招募）
不适用
Morphine or paracetamol as pain medication in children after open heart surgeryEUCTR2015-001835-20-NLErasmus MC
进行中（未招募）
不适用
Morphine intravenous vs. Paracetamol intravenous in children on ECMO - Morphine iv vs. paracetamol iv in children on ECMOPatients treated with Extra Corporal Membrane Oxygenation (ECMO) receive morphine as standardised analgesic drug. Morphine is associated with several side effects. In these patients a non-opioid drug could be effective for postoperative pain relief of ECMO cannula insertion and during ECMO treatment. When pre-ECMO analgesics are stopped after cannulation, intermittent administration of intravenous paracetamol to children during the ECMO run, will lead to a 25% reduction of morphine consumption.EUCTR2009-014892-31-NLErasmusMC - Sophia
已完成
不适用
Morphine intravenous vs. Acetaminophen intravenous in neonates and young infants undergoing major non-cardiac surgery.AnalgesieNociceptionpainNL-OMON31857Erasmus MC, Universitair Medisch Centrum Rotterdam72
进行中（未招募）
不适用
Morphine intravenous vs. Acetaminophen intravenous in neonates and young infants undergoing major non-cardiac surgery. - Morphine iv vs. Acetaminophen ivPatients after non-cardiac thoracic or abdominal major surgery receive Morphine as pain relief medication whereas this is associated with Morphine related side effects. In these patients a non-opioid drug could be appropriate for postoperative pain relief. Intermittent administration of intravenous Acetaminophen, to young infants up to 48 hrs after major surgery e.g. thoracic and abdominal, will lead to a clinically significant (>30%) morphine sparing effectEUCTR2007-005619-24-NLErasmusmMC/ Sophia Children Hospital
已完成
不适用
Effect of Paracetamol on Postop PaiCholecystectomy.Acquired absence of other parts of digestive tractIRCT2013012712298N1Qazvin University Of Medical Scienses70