ACTRN12618001327279
Withdrawn
未知
sing Molecular Plaque Imaging to Ascertain Cardiovascular Risk in Patients with Sleep Apnoea
South Australian Health and Medical Research Institute (SAHMRI)0 sites50 target enrollmentAugust 7, 2018
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Atherosclerotic Cardiovascular Disease
- Sponsor
- South Australian Health and Medical Research Institute (SAHMRI)
- Enrollment
- 50
- Status
- Withdrawn
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •a.Able to provide written, informed consent
- •b.Age greater than or equal to 40 years of age
- •c.Evidence of established atherosclerotic cardiovascular disease
- •As evident by
- •i.History of myocardial infarction
- •ii.acute coronary syndrome
- •iii.arterial revascularization
- •Risk Factor (One Required)
- •i.Cigarette smoking current?
- •ii.Hypertension (BP greater than or equal to 140/90 mm Hg or current use of antihypertensive medication)?
Exclusion Criteria
- •a.Inability to provide written, informed consent
- •b.Unwilling to undergo PET\-CT imaging
- •c.Treated with chronic anti\-inflammatory agents (immunosuppressants, oral corticosteroids)
- •d.Chronic kidney disease (use of dialysis or eGRF \<50 mL/min)
- •e.Subjects with uncontrolled diabetes defined as HbA1c \> 13 % in the last 3 months
- •f.insulin treatment for diabetes mellitus
- •g.Systemic inflammatory or autoimmune disease
- •h.Prior aortic or carotid surgery
- •i.Prior use of CPAP for OSA in the last 12 months
- •j.Female participants cannot be pregnant or breast\-feeding
Outcomes
Primary Outcomes
Not specified
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