NL-OMON42178
Completed
Not Applicable
ovel noninvasive molecular imaging modalities for ischemia in peripheral arterial disease - MR modalities for PAD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- exertional leg pain
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 50
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- ongoing reversible exertional pain in the lower right and/or left leg (Fontaine 2b)
- •\- ongoing rest pain in the lower right and/or left leg (Fontaine 3\) (if possible)
- •\- age 40 years or older;healthy volunteers:
- •\- no history of cardiovascular disease
- •\- no cardiovascular risk factors
Exclusion Criteria
- •for all groups:
- •\- history of muscular diseases
- •\- diabetes mellitus
- •\- metabolic diseases
- •\- (locomotor) neurologic abnormalities or diseases
- •\- known systemic disorders
- •\- standard contraindications for MRI;healthy controls: use of any cardiovascular medication, including but not limited to lipid\-lowering therapy, antihypertensive drugs, antidiabetic drugs, platelet aggregation inhibitors and anticoagulants
Outcomes
Primary Outcomes
Not specified
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