Molecular imaging for the early diagnosis and monitoring of Alzheimer’s disease in old individuals with cognitive disturbances: an ADNI-compatible prospective study - 09/2011 Molecular Imaging

IRCCS CENTRO SAN GIOVANNI DI DIO0 sitesMarch 1, 2012

Overview

No summary available.

Registry

who.int

Start Date

March 1, 2012

End Date

TBD

Last Updated

12 years ago

Study Type

Interventional clinical trial of medicinal product

Sex

All

Sponsor

IRCCS CENTRO SAN GIOVANNI DI DIO

•\-Male and female aged between 55\-90 years; \-Memory complains reflecting a change in cognition reported by patient or informant or clinician; \-Presence of objective memory or other cognitive domain impairment; \-General cognition and functional performance sufficiently preserved such that a diagnosis of Alzheimer’s disease cannot be made by the site physician at the time of the screening visit; \-Mini\-Mental State Exam score between 24 and 30 (inclusive); \-Clinical Dementia Rating \= 0\.5\. Memory Box score must be at least 0\.5; \-Amnestic Mild Cognitive Impairment (MCI) (pure amnestic or multidomain); \-At least 5 grades education. \-Written informed consent
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1\.2 Adults (18\-64 years) yes
•F.1\.2\.1 Number of subjects for this age range 15
•F.1\.3 Elderly (\>\=65 years) yes
•F.1\.3\.1 Number of subjects for this age range 85

•\-Visual and auditory acuity inadequate for neuropsychological testing; \-History of significant neurological or psychiatric illnesses or presence of other diseases precluding enrolment; \-The chronic use of anti\-inflammatory drugs \-Female subjects of child\-bearing potential with a positive pregnancy test; \-Female subjects who are nursing;