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Study of ONO-2506 in Patients With Acute Ischemic Stroke

Phase 2
Completed
Conditions
Stroke
Interventions
Drug: ONO-2506
Registration Number
NCT00229177
Lead Sponsor
Ono Pharmaceutical Co. Ltd
Brief Summary

The purpose of this study is to determine the efficacy and safety of ONO-2506 compared to placebo in patients with acute ischemic stroke.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
757
Inclusion Criteria
  1. Subjects who have a clinical diagnosis of acute ischemic stroke
  2. Subjects within 72 hours after onset of the stroke
  3. Other inclusion criteria may apply.
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Exclusion Criteria
  1. Subjects who are scheduled to have surgical operations likely to affect the prognosis (including intravascular surgery and circulatory reconstruction)
  2. Subjects who are pregnant or lactating, or who have child-bearing potential, or who wish to become pregnant.
  3. Other exclusion criteria may apply.
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
PONO-2506-
E2ONO-2506-
E1ONO-2506-
Primary Outcome Measures
NameTimeMethod
Modified Rankin Scale at 90 days90 days
Secondary Outcome Measures
NameTimeMethod
Modified Rankin Scale at 30 days30 days
National Institutes of Health Stroke Scale (NIHSS), Barthel Index (BI), and Glasgow Outcome Scale (GOS) at 90 days90 days

Trial Locations

Locations (9)

Kinki Region Facility

🇯🇵

Kinki, Japan

Chubu Region Facility

🇯🇵

Chubu, Japan

Chugoku Region Facility

🇯🇵

Chugoku, Japan

Hokuriku Region Facility

🇯🇵

Hokuriku, Japan

Hokkaido Region Facility

🇯🇵

Hokkaido, Japan

Kyushu Region Facility

🇯🇵

Kyushu, Japan

Kanto Region Facility

🇯🇵

Kanto, Japan

Shikoku Region Facility

🇯🇵

Shikoku, Japan

Tohoku Region Facility

🇯🇵

Tohuku, Japan

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