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Clinical Trials/NCT01821417
NCT01821417
Completed
Not Applicable

A Randomized Clinical Trial to Assess the Performance of MicroTextured Dental Implants With or Without a Machined Collar

University of Alabama at Birmingham1 site in 1 country68 target enrollmentMay 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Partially Edentulous Jaw
Sponsor
University of Alabama at Birmingham
Enrollment
68
Locations
1
Primary Endpoint
Change in Millimeters of Bone Loss Surrounding the Implant Device
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The study will compare initial peri-implant bone healing and longitudinal osseointegration between a fully microtextured dental implant and an analogous implant with a smooth machined collar.

The investigators hypothesize the fully textured implant will result in less peri-implant crestal bone resorption than the implant with a machined collar.

Detailed Description

Zimmer dental has developed a microtextured tapered screw-vent implant design with a titanium skin that has been grit-blasted with hydroxyapatite particles resulting in an overall roughened surface, which, when compared to an implant with a machined (smooth) collar (narrow band around the top of the device) surface is thought to increase the apposition of osseous tissue integration and to promote epithelial attachment to the implant device.

Registry
clinicaltrials.gov
Start Date
May 2011
End Date
October 2015
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Michael Reddy, DMD

Professor

University of Alabama at Birmingham

Eligibility Criteria

Inclusion Criteria

  • Be a current registered University of Alabama at Birmingham (UAB)dental school patient
  • Existence of one or more missing teeth scheduled to be replaced with dental implants
  • Healthy enough to undergo proposed therapy without compromising existing health
  • Able to consent for their own inclusion
  • Able to read and understand the informed consent form
  • Demonstrated willingness to comply with protocol requirements and timeline

Exclusion Criteria

  • Any health condition that in the opinion of the investigators may adversely affect bone healing
  • Any medication that in the opinion of the investigators may adversely affect bone healing
  • Any indication of an inability to make autonomous decisions
  • Reported pregnancy at the time of enrollment -

Outcomes

Primary Outcomes

Change in Millimeters of Bone Loss Surrounding the Implant Device

Time Frame: Implant insertion, 12 months post-insertion

Using radiographic images and image-processing software, measurements of bone height at the mesial and distal of each implant will be captured in millimeters.

Secondary Outcomes

  • Changes in Peri-implant Gingivitis Score(1 year after placement)
  • Millimeters of Periodontal Pocket Depth Surrounding the Dental Implant Device(1 year after placement)

Study Sites (1)

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