NCT04851548Unknown不适用
Evaluate the Effectiveness of Bioactive Hyaluronic Acid in the Treatment of Furcation Involvement
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 18
- 主要终点
- evaluate the regenerative effect of hyaluronic acid
研究概览
简要总结
the effect Hyaluronic Acid in the Treatment of Furcation Involvement
详细描述
The materials to be used in the study are the following:
- Hyaluronic acid
- Cone-beam computed tomography(CBCT) x-ray The patients with Grade II furcation will be divided into two groups. Both groups will have the same number of patients and the same procedure, such as the scaling root planning. However, the control group will use hyaluronic acid and membrane. The placebo group, on the other hand, will use hyaluronic acid without membrane and will use CBCT x-ray. The x-rays will be done at the beginning of the treatment. Then, two monitoring processes will be done. The first monitor will be done after three months. The data will be recorded. Then, after another three months, the patients will undergo an x-ray check again, and the data will be recorded. The goal is only to have the patients exposed to x-ray twice so they would not be compromised to the high dose of radiation. The evaluation to be done for the 3-month interval will only be clinical assessments.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Selected teeth: Permanent first and second molars in the mandible.
- •Furcation dimension: Radiographic and clinical evidence of exhibiting defects due to Grade II furcation with at least 2 millimeters probing depth horizontally and at least 5 millimeters probing depth circumferential.
- •Gender: both males and females.
- •Age range: between 18 and 55 years.
- •Health status: healthy patients non-systemic diseased except controlled diabetic.
- •Compliance: Patients will be willing and able to comply with adequate oral hygiene protocols.
排除标准
- •Patients that received periodontal regenerative therapy within the past 12 months.
- •Patients that are lactating.
- •Pregnant patients.
- •Patients with pulp infection.
- •Patients with trauma resulting from occlusion.
- •Patients with receding gum.
- •Patients with tooth mobility greater than grade II.
- •Patients that will not comply with the hygiene protocols in Phase I therapy.
- •Patients with potential illnesses that can influence the periodontal therapy outcomes.
- •Patients that are taking medications that can interfere with the healing outcomes of the periodontal wound.
- •Patients allergic to any drugs.
结局指标
主要结局
evaluate the regenerative effect of hyaluronic acid
时间窗: 6 months
measurement of the bone gain after the treatment with hyaluronic acid in millimeters
次要结局
未报告次要终点
研究者
Ghady Adnan Alqahtani
periodontic resident
Riyadh Elm University
相似试验
已完成
不适用
Reconstruction of Interdental Papilla Using Hyaluronic AcidDefected Interdental PapillaNCT02119741Damascus University30
尚未招募
4 期
A study to evaluate the effectiveness of hyaluronic acid for managing the complications occurring after removal of impacted mandibular third molar.CTRI/2023/05/053278Dr Alfisha Sheikh
招募中
4 期
Hyaluronic Acid for the Treatment of Damaged Nipples in Breastfeeding WomenCracked NippleBreastfeedingHealing WoundNCT05591651Specijalisticka Pedijatrijska Ordinacija prim.mr.sc. Maja Stimac, Specijalist Pedijatrije Sspecijalnosti Neonatologije160
已完成
4 期
Effect of Topically-Applied Hyaluronic-Acid on Palatal Epithelial Wound ClosureWound Healing ComplicationNCT02534415Marmara University36
Unknown
3 期
Role of Hyaluronic Acid in the Prevention of Post-operative Adhesions: a RCTPost Operative AdhesionsNCT02790177Services Institute of Medical Sciences, Pakistan150