Individual Dietary Counseling Based on Taste-tests in Patients With Hematological Cancer in Cytostatic Therapy

Not Applicable

• Conditions: Hematological Malignancy
• Interventions: Other: Standard care; Dietary Supplement: Taste-test

• Registration Number: NCT05364359
• Lead Sponsor: University of Copenhagen

Brief Summary

The purpose of the study is to investigate whether a simple taste-test will increase the intake of energy as part of the individual dietary counseling.

Detailed Description

The investigators will investigate the tastes (umami, bitter, salty, sweet and sour) that the patients prefers in order to increase the energy intake and reduce the risk of weight loss and loss of fat-free mass for patients with hematological cancer.

The study will be conducted as a single blinded randomized controlled trial. 40 patients will be recruited, and will be divided into two groups; the intervention group and the control group. The patients will not know which group they belong to.

Study Timeline

• Study First Submitted: 2022-03-23
• Study Start: 2022-03-28
• Status Verified: 2022-05
• Study First Submitted QC: 2022-05-05
• Last Update Submitted: 2022-05-05
• Study First Posted: 2022-05-06
• Last Update Posted: 2022-05-06
• Primary Completion: 2022-07-28
• Study Completion: 2022-08-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• 18 years or older
• Able to understand the "Participant Information" paper
• Diagnosed with hematological cancer
• Must be undergoing chemotherapy (at least one treatment during the study)
• Outpatient
• Be able to take pictures of meals (and send to the sub-investigators)
• Be able to speak and read the danish language

Exclusion Criteria

• Pacemaker

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Standard dietary counseling	Standard care	The patients will receive a individual standard dietary counseling not based on the taste-test
Intervention group	Taste-test	The patients will receive a individual dietary counseling based on the taste-test

Primary Outcome Measures

Name	Time	Method
Consumption of energy as a percentage of estimated need	6 weeks	difference - before and after intervention

Secondary Outcome Measures

Name	Time	Method
Hand-grip-strength (measured with a dynamometer)	6 weeks	difference - before and after intervention
Body weight	6 weeks	difference - before and after intervention
Fat-free-mass and fat-mass in percent (bioimpedance measurement)	6 weeks	difference - before and after intervention
Satisfaction (measured with EROTC QLQ-C30 version 3.0)	6 weeks	difference - before and after intervention. Higher scores means worse outcome. Lower scores means better outcomes.
Protein intake	6 weeks	difference - before and after intervention
Burning/pain in the mouth (measured on a scale)	6 weeks	difference - before and after intervention measured with Likert scale (1 to 5). Higher scores means a worse outcome. Lower scores means better outcomes.

Trial Locations

Locations (1)

Department of Hematology; 🇩🇰 Roskilde, Denmark