Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) for colorectal cancer screening
Completed
- Conditions
- Colorectal cancercolon cancer1001799010017991
- Registration Number
- NL-OMON33589
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 390
Inclusion Criteria
-Patients who are planned to undergo a colonoscopy in the UMC Utrecht because of suspected colorectal cancer, and having at least one of the following symptoms/signs: rectal bleeding, change in bowel habit, inexplicable weight loss, abdominal pain, and/or anemia
-Age: 50 years and older
-Written informed consent
Exclusion Criteria
-Patients with a general contraindication for MRI (including cardiovascular pacemakers, claustrophobia)
-Patients who have had a previous malignancy
-Patients who are pregnant or nursing
-Patients in whom therapy has already started
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Sensitivity, specificity, positive predictive value and negative predictive<br /><br>value of DWIBS (with 95% confidence intervals) for the detection of relevant<br /><br>colorectal lesions (carcinomas and polyps >= 6mm).</p><br>
- Secondary Outcome Measures
Name Time Method <p>N.A.</p><br>