An Observational Study of Avastin (Bevacizumab) in Elderly Patients With Non-Squamous Non-Small Cell Lung Cancer in Clinical Practice
- Conditions
- Non-Squamous Non-Small Cell Lung Cancer
- Registration Number
- NCT01893268
- Lead Sponsor
- Hoffmann-La Roche
- Brief Summary
This prospective, observational study will assess the effectiveness and safety of Avastin (bevacizumab) as 1st line therapy in elderly patients with advanced non-squamous non-small cell lung cancer in clinical practice. Therapy with Avastin and standard chemotherapy will be administered according to the treating physician. Data will be collected for approximately 4 years.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 279
- Adult patients, >= 65 years of age
- Diagnosis of advanced non squamous Non-Small Cell Lung Carcinoma (nsNSCLC, stage IIIB or IV) for whom the physician has decided to initiate a treatment with Avastin combined with chemotherapy as 1st line therapy
- Having received oral and written information about the study, and having signed a written consent form
- Participation in a cancer clinical trial with an investigational medicinal product other than this study
- Patient previously treated with Avastin
- Patient under supervision or guardianship
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of patients treated with a chemotherapy in combination with Avastin including description of chemotherapy regimens and management of Avastin treatment Approximately 4 years
- Secondary Outcome Measures
Name Time Method Characteristics of patients with advanced non-squamous non-small cell lung cancer Approximately 4 years Tumor characteristics of patients with advanced non-squamous non-small cell lung cancer Approximately 4 years Progression-free survival Approximately 4 years Overall survival Approximately 4 years Quality of Life Approximately 4 years Safety: Incidence of adverse events Approximately 4 years Reasons of non-use of Avastin as first-line therapy Approximately 4 years
Trial Locations
- Locations (85)
Clinique Du Docteur Calabet; Cromg
🇫🇷Agen, France
Poly Parc Rambot La Provencale; Chimiotherapie Ambulatoire
🇫🇷Aix En Provence, France
HOPITAL JEAN MINJOZ; Oncologie
🇫🇷Besancon, France
Ch De Chauny; Pneumologie
🇫🇷Chauny, France
CH Du Cotentin Site De Cherbourg; Hopital De Jour
🇫🇷Cherbourg Octeville, France
Ch De La Dracenie; Pneumologie
🇫🇷Draguignan, France
Hopital Gabriel Montpied; Service de Pneumologie
🇫🇷Clermont-ferrand, France
Hopital Louis Pasteur; Pneumologie Tabacologie
🇫🇷Colmar, France
CH Emmanuel Rain; Oncologie
🇫🇷Gonesse, France
Hopital Prive De Chantilly; Medecine
🇫🇷Gouvieux Chantilly, France
Hopital D Hayange;Medecine A Et P
🇫🇷Hyeres, France
Hopital Calmette; Pneumologie Oncologie Ouest
🇫🇷Lille, France
Centre Oscar Lambret; Chir Cancerologie General
🇫🇷Lille, France
Clinique Chenieux; Oncology
🇫🇷Limoges, France
Centre Hospitalier Général; Pneumologie
🇫🇷Longjumeau, France
Hopital Du Cluzeau; Service de Pathologie Respiratoire
🇫🇷Limoges, France
Hopital Dupuytren; Pneumologie
🇫🇷Limoges, France
Polyclinique Gentilly; CHIMIOTHERAPIE AMBULATOIRE
🇫🇷Nancy, France
Hopital Saint Louis; Oncologie Medicale
🇫🇷Paris, France
Clinique sainte marie; chimiotherapie ambulatoire
🇫🇷Osny, France
CH Rene Dubos; Oncologie
🇫🇷Pontoise, France
Clinique Saint Hilaire; Sce Chimiotherapie
🇫🇷Rouen, France
Hopital Laennec; Service de Pneumologie
🇫🇷Quimper, France
Cabinet
🇫🇷Reims, France
Hopital de Pontchaillou; Service de Pneumologie
🇫🇷Rennes, France
Ch De Saint Quentin; Medecine B14
🇫🇷St Quentin, France
Hopital Bel Air; Pneumologie Allergologie
🇫🇷Thionville, France
Hopitaux Du Leman Site Thonon; Pneumologie
🇫🇷Thonon-les-bains, France
Hopital Sainte Musse; Pneumologie
🇫🇷Toulon, France
Clinique Pasteur; Pneumologie
🇫🇷Toulouse, France
Hopital Des Hauts Clos; Pneumologie
🇫🇷Troyes, France
Ch De Valence; Medecine 7
🇫🇷Valence, France
Hopital Saint Nicolas; Pneumologie
🇫🇷Verdun, France
Hopital Robert Schuman; Pneumologie
🇫🇷Vantoux, France
Centre Alexis Vautrin; Oncologie Medicale
🇫🇷Vandoeuvre Les Nancy, France
Gh Mutualiste Les Portes Du Sud; Pneumologie
🇫🇷Venissieux, France
Cabinet Medical
🇫🇷Tours, France
Ch De Beziers; Pneumologie
🇫🇷Beziers, France
Hopital Avicenne; Cancerologie
🇫🇷Bobigny, France
Centre D Oncologie Dunkerquois
🇫🇷Dunkerque, France
Chi Emile Durkheim Site Epinal; Pneumologie
🇫🇷Epinal, France
Hopital Cochin; Unite Fonctionnelle D Oncologie
🇫🇷Paris, France
Hopital Europeen Georges Pompidou; Service D'Oncologie Medicale
🇫🇷Paris, France
Centre Catalan D' Oncologie
🇫🇷Perpignan, France
Ch De Saintonge; Unite 2 Pneumologie
🇫🇷Saintes, France
Centre Medical National Mgen; Pneumologie
🇫🇷Ste Feyre, France
Centre Paul Strauss; Oncologie Medicale
🇫🇷Strasbourg, France
Ch Du Pays D Aix; Pneumologie
🇫🇷Aix En Provence, France
Centre Hospitalier Uni Ire; Pneumology
🇫🇷Angers, France
Chic Cote Basque Bayonne; Pneumologie
🇫🇷Bayonne, France
Hopital Louis Pradel; Pneumologie
🇫🇷Bron, France
CH Germon ET Gauthier; Pneumologie
🇫🇷Beuvry, France
Polyclinique Bordeaux Nord Aquitaine; Chimiotherapie Radiotherapie
🇫🇷Bordeaux, France
Centre Hospitalier Fleyriat; Oncologie/Hematologie
🇫🇷Bourg En Bresse, France
Ch De Brive La Gaillarde; Radiotherapie Oncologie
🇫🇷Brive La Gaillarde, France
Ch De Fleyriat; Pneumologie 1
🇫🇷Bourg En Bresse, France
Hia Clermont Tonnerre; Pneumologie
🇫🇷Brest, France
Hopital Pierre Nouveau; Pneumologie
🇫🇷Cannes, France
Ch Antoine Gayraud; Oncologie
🇫🇷Carcassonne, France
Clinique Du Parc; Hematologie
🇫🇷Castelnau Lez, France
Ctre Medical Nicolas de Pontoux
🇫🇷Chalon Sur Saone, France
Clinique Des Cedres; Pneumologie
🇫🇷Cornebarrieu, France
Centre Jean Perrin; Hopital De Semaine
🇫🇷Clermont-Ferrand, France
Centre Hospitalier Alpes Leman CHAL;Pneumologie
🇫🇷Contamine Sur Arve, France
Centre Hospitalier Intercommunal; Service de Pneumologie
🇫🇷Creteil, France
Chu Site Du Bocage;Pneumologie
🇫🇷Dijon, France
Chi Alpes Du Sud Site De Gap; Pneumologie
🇫🇷GAP, France
Hopital Nord Ouest;Unite 2c
🇫🇷Gleize, France
Hopital Saint Vincent; Consult et Explorations
🇫🇷Lille, France
Hopital Layne; Medecine Ambulatoire
🇫🇷Mont-de-marsan, France
Ch Bretagne Sud Site Scorff; Oncologie Medicale
🇫🇷Lorient, France
Centre Hospitalier François Quesnay; Pneumologie-Neurologie
🇫🇷Mantes La Jolie, France
Hôpital Saint Joseph; Oncologie Medicale
🇫🇷Marseille, France
Centre Hospitalier; Pneumologie
🇫🇷Metz Tessy, France
Ch De Montauban; Pneumologie
🇫🇷Montauban, France
Hopital Emile Muller;Pneumologie
🇫🇷Mulhouse, France
Hopital Caremeau; Pneumologie
🇫🇷Nimes, France
Centre Medical Parot
🇫🇷Lyon, France
Centre Hospitalier Lyon Sud; Pneumologie
🇫🇷Pierre Benite, France
Ch De Rambouillet; Pneumologie Cardiologie
🇫🇷Rambouillet, France
Centre Cardiologique Du Nord; Pneumologie
🇫🇷Saint Denis, France
Clinique de L'Union; Oncologie
🇫🇷Saint Jean, France
Hopital Nord; Service de Pneumologie
🇫🇷Saint Priest En Jarez, France
Hia Sainte Anne; Pneumologie
🇫🇷Toulon, France
Groupe Oncorad Garonne; Unite Onco Hematologie
🇫🇷Toulouse, France