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An Observational Study of Avastin (Bevacizumab) in First Line in Patients With Metastatic Colorectal Cancer (AVANiS)

Completed
Conditions
Colorectal Cancer
Registration Number
NCT01674907
Lead Sponsor
Hoffmann-La Roche
Brief Summary

This observational study will evaluate the use in clinical practice and the efficacy of Avastin (bevacizumab) in patients with metastatic colorectal cancer who have not received prior chemotherapy treatment in the metastatic setting. Patients for whom the treating physician has decided to initiate therapy with Avastin will be followed for 10 months.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
27
Inclusion Criteria
  • Adult patients, >/= 18 years of age
  • Histologically confirmed metastatic colorectal cancer without prior chemotherapy in the metastatic setting
Exclusion Criteria
  • Contraindications for Avastin according to the locally approved package insert (version 7 April 2006)

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Clinical/demographic patient characteristics at baselineapproximately 3 years
Dosage/schedule of 1st-line Avastinapproximately 3 years
Chemotherapy regimens used in clinical practiceapproximately 3 years
Duration of treatmentapproximately 3 years
Secondary Outcome Measures
NameTimeMethod
Relationship between termination of Avastin treatment and time point of progressionapproximately 3 years
Progression-free survivalapproximately 3 years
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