NCT01827852已完成不适用
AVAdeno: Non-interventional Study of Avastin 1st Line Therapy in Adenocarcinoma Patients of the Lung
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,107
- 试验地点
- 1
- 主要终点
- Progression-free survival in 4 different age groups (<60, 60-69, 70-79, >/=80 years)
研究概览
简要总结
This prospective observational study will evaluate the efficacy and safety of first-line Avastin (bevacizumab) in combination with platinum-based chemotherapy in different age groups (<60, 60-69, 70-79, >80 years) in patients with inoperable advanced, metastatic or recurrent adenocarcinoma non-small cell lung cancer. Patients will be followed for 18 months from the start of first-line therapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients, >/= 18 years of age
- •Histologically confirmed inoperable advanced, metastatic or recurrent pre-dominantly non-squamous adenocarcinoma non-small cell lung cancer
排除标准
- •Contraindications to Avastin treatment according to the Summary of Product Characteristics
结局指标
主要结局
Progression-free survival in 4 different age groups (<60, 60-69, 70-79, >/=80 years)
时间窗: approximately 4.5 years
次要结局
- Clinical/demographic patient characteristics at initiation of treatment(approximately 4.5 years)
- Concomitant anti-neoplastic therapy (dosage/duration)(approximately 4.5 years)
- Overall survival in 4 different age groups (<60, 60-69, 70-79, >/=80 years)(approximately 4.5 years)
- Safety: Incidence of adverse events in 4 different age groups (<60, 60-69, 70-79, >/=80 years)(approximately 4.5 years)
- Avastin treatment schedule in routine clinical practice (dosage/duration)(approximately 4 years)
研究者
研究点 (1)
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