DRKS00017793已完成不适用
The function of the endocrinological oxytocin system under psychosocial stress conditions in adolescents with anxiety disorder
Klinik und Poliklinik für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie der Universität Regensburg am Bezirksklinikum Regensburg0 个研究点目标入组 64 人开始时间: 2019年9月11日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 64
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 11 Years 至 18 Years（—）
- 性别
- All
入选标准
- •General inclusion criteria of the index and control group
- •Sufficient understanding of the German language
- •Informed consent of study participants and their legal guardians
- •Age at baseline: 11-18 years
- •School education: middle school, junior high school, high school
- •Good connection to in- and outpatient diagnostic/medical consultation/ treatment at the Clinic for Child and Adolescent Psychiatry Regensburg.
- •Inclusion criteria index group
- •Anxiety disorder according to the diagnostic criteria of the DSM-5 classification and ICD-10 Agoraphobia (ICD-10 F40.0) with/without a panic disorder (F40.00, F40.01), social phobias (F40.1), panic disorder (F41.0), generalized anxiety disorder (F41.1), separation anxiety disorder of childhood (F93.0), social (F93.2) and generalized (F93.80) anxiety disorder of childhood.
- •No further psychiatric comorbidities (except for mild depressive disorder, moderate depressive disorder (ICD-10 F32.0. F32.1))
- •Inclusion criteria control group
- •No history of psychiatric and neurological diseases
- •No current and history of in- and outpatient psychiatric and psychotherapeutic treatment and any psychiatric disorder
排除标准
- •General exclusion criteria of the index group and control group
- •History of traumatic brain injury, history of endocrinological disorder, any other chronic neurological or other disorder, which influences the brain development and physiology
- •Current glucocorticoid-containing medication
- •Pregnancy
- •Early pubertal development (Pubertas präcox vera) due to an abnormal hormone status (Brämswig & Dübbers, 2009)
- •Intellectual impairment (IQ <85)
- •School education: special school
- •Acute psychotic disorder or acute psychiatric condition, which may affect the capacity to consent
- •Acute suicidality
- •Lack of consent
- •Exclusion criteria control group
- •Anxiety score after answering the test questionnaires above the reference values defined by the respective test criteria and guidelines for evaluation
- •Diagnosed anxiety disorder according to DSM-5 and ICD-10 criteria
- •Any current or history of psychiatric and neurological disorder, which requires medical treatment
- •Current and history of in- and outpatient psychiatric and psychotherapeutic treatment
研究者
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