Effects of Prebiotic-based Snacks on the Gut Microbiota and Perceived 'Satisfaction'
- Conditions
- Obesity
- Interventions
- Dietary Supplement: Nutriose FB06Dietary Supplement: Placebo
- Registration Number
- NCT02041975
- Lead Sponsor
- University of Reading
- Brief Summary
To determine the effects of prebiotic 'snacks' on gut health and satisfaction between meals
- Detailed Description
The role of the bacteria that reside in the human gut play in human health and disease is of increasing importance. Evidence gathered over recent decades' shows that certain bacteria can improve resistance to gut infections, reduce cholesterol levels, synthesise vitamins and improve the immune response. The potential to modulate the relative balance of these so-called 'beneficial' bacteria has been demonstrated through the use of certain fibre sources termed prebiotics. In addition there is interest to understand how snacks containing these fibre sources may affect levels of 'satisfaction' between meals. The current study will address these issues and lead to a greater understanding of the role that prebiotics may play in gut health and overall metabolism.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 47
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Prebiotic Nutriose FB06 Nutriose FB06 14g/day Placebo Placebo Maltodextrin
- Primary Outcome Measures
Name Time Method Differences in perceived appetite (assessed using visual analogue scales) Within 18 months
- Secondary Outcome Measures
Name Time Method Alterations to the relative balance of bacterial groups in faeces (assessed using flow cytometry) Within 18 months
Trial Locations
- Locations (1)
University of Reading
🇬🇧Reading, Berkshire, United Kingdom