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Clinical Trials/NCT05822635
NCT05822635
Completed
Not Applicable

Intraoperative Endoscopy Using a Thin, Single-Use, Flexible Cholangiopancreatoscope

Boston Scientific Corporation5 sites in 4 countries34 target enrollmentDecember 1, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pancreatic Diseases
Sponsor
Boston Scientific Corporation
Enrollment
34
Locations
5
Primary Endpoint
Technical success
Status
Completed
Last Updated
last year

Overview

Brief Summary

  • To document the clinical utility of diagnostic and/or therapeutic intraoperative endoscopy using a thin, single-use, flexible cholangiopancreatoscope
  • To identify specific surgical procedures in which intraoperative use of a thin, single use, flexible cholangiopancreatoscope suggests clinically meaningful benefit and generate a hypothesis for possible subsequent claims-supportive study

Detailed Description

This case series aims to document the clinical utility of intraoperative endoscopy using a thin, disposable, flexible cholangiopancreatoscope in procedures including but not limited to: * Evaluation of biliary lesion(s) during surgical management of common bile duct (CBD) and intrahepatic duct (IHD) strictures, with or without biopsy * Transcystic/transcholedochal clearance of biliary stone(s)/sludge/cast with or without mechanical, electrohydraulic or laser lithotripsy * Treatment of hepatolithiasis * Assessment of communication between the biliary tree and the cyst in the setting of ruptured hydatid parasitic cysts or abcesses * Visualization of intraductal papillary mucinous neoplasm (IPMN) lesion(s) with or without biopsy * Assessment of pancreatic duct (PD) strictures in chronic pancreatitis, with or without biopsy

Registry
clinicaltrials.gov
Start Date
December 1, 2023
End Date
January 3, 2025
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Clinical indication for intraoperative endoscopy using a thin, single-use, flexible cholangiopancreatoscope
  • Written informed consent from patient or legally authorized representative of the patient

Exclusion Criteria

  • Contraindication for intraoperative endoscopy using a thin, single-use, flexible cholangiopancreatoscope
  • \<18 years of age
  • Potentially vulnerable subjects, including, but not limited to pregnant women

Outcomes

Primary Outcomes

Technical success

Time Frame: During study procedure

Perform intraoperative endoscopy as intended using a thin, single-use, flexible cholangiopancreatoscope as desired, including but not limited to: * Direct visualization of target lesion or stricture * Obtaining biopsies * Initiating and/or completing stone clearance

Secondary Outcomes

  • Number of adverse events(1 month)
  • Endoscopist rating of clinical impact of study procedure(During study procedure)
  • Endoscopist rating of device(During study procedure)
  • Adequate diagnostic yield(1 month)

Study Sites (5)

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