Preserving Vitality- Comparative evaluation of three bioactive materials used in pulpotomy of mature permanent teeth
Trial Snapshot
- Phase
- Phase 2
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 45
- Locations
- 1
- Primary Endpoint
- Reduction of pain measured by VAS score
Study Overview
Brief Summary
Until recently, the pulp of mature tooth exposed by caries was considered as a "doomed organ", with pulp extirpitation and root canal treatment being the standard treatment protocol
In cases involving pulp exposure to the level of coronal pulp, pulpotomy has emerged as a treatment protocol as it aids in preserving the vitality of the tooth
Preservation of pulpal vitality of of paramount importance as vital functioning of pulp is capable of initiating several important functions such as formation of dentin, providing nutritive support, enabling a defensive function and possessing a unique regenerative capacity
Pulpotomy is a procedure which involves removal of inflammed coronal pulpal tissue and replacing it with a suitable material, leaving vital radicular pulp within the canals
The advent of newer bioactive materials like Mineral Trioxide Aggregate (MTA), Biodentine and bioceramics have significantly increased the prognosis of vital pulp therapy
The aim of this study is to evaluate and compare performance of three different bioactive materials as pulpotomy agents in mature permanent molars
Study Design
- Study Type
- Interventional
- Allocation
- Coin toss, Lottery, toss of dice, shuffling cards etc
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Mandibular molars with caries extending to pulp and having symptoms of irreversible pulpitis with positive response to vitality tests (Cold test+EPT).
Exclusion Criteria
- •Teeth that will not respond to vitality tests (Cold+EPT) Teeth with periapical involvement Individuals having Systemic diseases or on antibiotics Teeth having excessive bleeding after cavity preparation (Haemostasis not achieved within 5 minutes of coronal pulp removal).
Outcomes
Primary Outcomes
Reduction of pain measured by VAS score
Time Frame: Baseline
Secondary Outcomes
- Elimination of pain measured by VAS score(After 7 days, 1 month, 3 months, 6 months, 1 year)
- No pathosis evident on radiograph(After 7 days, 1 month, 3 months, 6 months, 1 year)
Investigators
Mohil Kale
College Of Dental Sciences And Research Center