Optimization of ASL MRI in healthy elderly, and validation with TCD and NIRS

Completed

• Conditions: er wordt niet gekeken naar een aandoening, maar naar de toepassing van de techniek; cerebral blood flow; cerebral perfusion

• Registration Number: NL-OMON37114
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2014-03-31
• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 4

Inclusion Criteria

healthy elderly aged over 50 years, MMSE score over 25

Exclusion Criteria

neurological or psychiatric disorders
contraindication for MRI (metal implantates, claustrophobia)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>CBF measured with ASL (ml/100 gr/min), and cerebral auto regulation measured<br /><br>with TCD (cm/s), NIRS (concentration oxy/deoxy Hb in mmol/L) </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>non</p><br>