A prospective study on the role of the cerebellar flocculus in tinnitus: the effect of surgical manipulation and tumor presence and the relation with electrophysiological and infection parameters

niversity Medical Center Groningen0 个研究点目标入组 100 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

•In order to be eligible to participate in this study, a subject must meet all of the following criteria:
•-Adult, aged 18 years or older;
•-Undergoing microvascular decompression for hemifacial spasms or trigeminal neuralgia or treatment of a CPA tumor (translabyrinthine/retrosigmoid surgical removal or radiotherapy);
•-Agree to participate in part 1 of this study
•-Psychosocially, mentally, and physically able to fully comply with this protocol, including adhering to scheduled visits, treatment plan, filling out questionnaires and undergoing tests.
•-Patient has sufficient mastery of the Dutch language to fill out the questionnaires.
•-Signed and dated informed consent document prior to any study-related procedures
•Patients meeting the following criterium will be asked to participate in part 2 and/or part 3 as well:
•-Undergoing retrosigmoid CPA tumor removal or the microvascular decompression for hemifacial spasms

•A potential subject who meets any of the following criteria will be excluded from participation in this study:
•-Suffering from bilateral CPA pathology (i.e. tumor or neurovascular conflict)
•-Bilateral complete deafness.
•-Presence of contra-indications for a MRI-scan.

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