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A prospective study on the role of the cerebellar (para)flocculus in tinnitus: the relation with electrophysiological parameters and inflammatory mediators

Recruiting
Conditions
hearing of sound when no external sound is present
Tinnitus
10019243
10029209
Registration Number
NL-OMON55531
Lead Sponsor
niversitair Medisch Centrum Groningen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
80
Inclusion Criteria

- Adult, aged 18 years or older;
- Undergoing microvascular decompression for hemifacial spasms or retrosigmoid
removal of a CPA tumor.
- Agrees to participate in the obligatory measurements of this study
- Psychosocially, mentally, and physically able to fully comply with this
protocol, including adhering to scheduled visits, treatment plan, filling out
questionnaires and undergoing tests.
- Patient has sufficient mastery of the Dutch language to fill out the
questionnaires.
- Signed and dated informed consent document prior to any study-related
procedures

Exclusion Criteria

- Suffering from bilateral CPA tumors
- Former surgery at the ipsi- or contralateral CPA region.
- Radiotherapy at the ipsi- or contralateral CPA region prior to surgery.
- Contralateral or bilateral complete deafness.
- Presence of pulsatile tinnitus synced with the heartbeat.

A potential subject who meets the following additional criterium will be
excluded from participation in module 2 of this study:
- Presence of a (chronic) inflammatory disease.

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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