Comparison of the effect of prophylactic bolus of ephedrine versus norepinephrine to prevent post-spinal hypotension during elelctive caesarean section under spinal anaesthesia.

Phase 1/2

Not yet recruiting

• Conditions: Obstetrics,

• Registration Number: CTRI/2024/01/061565
• Lead Sponsor: DrAkshata K Hiremath

Brief Summary

Comparision of the effect of prophylactic bolous dose of ephdrine versus norepinephrine to prevent post spinal hypotension in elective caesarean section -a randomised controlled double blind studydone on 50 persons in each group by computer generated randomisation in tertiary care teaching hospital.comparing mean arterial pressure ,heart rate bolus of vasopressors required ,apgar score and episodes of nausea and vomiting betwen two groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-20
• Last Update Posted: 2024-09-01

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

Willing to participate ASA class 2.

Exclusion Criteria

Pregnant women with pre-eclampsia and eclampsia Baseline bp>140mmhg BMI>30kg/m2 Comorbid conditions (cardiovascular, renal,hepatic diseases) Contraindication to spinal anaesthesia like coagulopathy,raised ICP Failed spinal anaesthesia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decreased incidence of post spinal hypotension with norepinephrine than ephedrine.	2 years

Secondary Outcome Measures

Name	Time	Method
Effective prevention of adverse effects like nausea, vomiting secondary to hypotension & improved neonatal outcome with norepinephrine than ephedrine.	2 years

Trial Locations

Locations (1)

SDM college of Medical Sciences and Hospital; 🇮🇳 Dharwad, KARNATAKA, India

SDM college of Medical Sciences and Hospital

🇮🇳Dharwad, KARNATAKA, India

Dr Akshata K Hiremath

Principal investigator

9035390094

Akshatakb97@gmail.com