Safety and Risk Assessment of Obese Parturient Underwent Cesarean Section(CS) Delivery Under General Anesthesia or Intraspinal Anesthesia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cesarean Section
- Sponsor
- Fudan University
- Enrollment
- 900
- Primary Endpoint
- Patients numbers of obese parturient complications
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
900 parturient who underwent CS under general anesthesia(GA) , intraspinal anesthesia included epidural anesthesia(EA) and combined spinal-epidural anesthesia(CSEA), which were divided into 3 groups: Morbid Obesity group (n=300) with body mass index (BMI) >40 kg/m2 , severe Obesity group (n=300) with 30 kg/m2≤BMI ≤40 kg/m2 and non-Obesity group(n=300) with BMI<30 kg/m2. Findings Between January 1, 2013 and September 30, 2016, a total of 1000 women met inclusion criteria and 900 women received allocated intervention. All patients were divided into three groups: Morbid Obesity group(n=300), Severe Obesity group(n=300) and non-Obesity group(n=300) according to body mass index (BMI) >40 kg/m2, 30 kg/m2≤BMI ≤40 kg/m2 and BMI<30 kg/m2.900 patients completed the protocol and related data were analysed.
Detailed Description
900 parturient who underwent CS under general anesthesia(GA) , intraspinal anesthesia included epidural anesthesia(EA) and combined spinal-epidural anesthesia(CSEA), which were divided into 3 groups
Investigators
Zeyong Yang
International Peace Maternity and Child Health Hospital
Shanghai Jiao Tong University School of Medicine
Eligibility Criteria
Inclusion Criteria
- •patients with ASA Physical Status gradeΙΙ～ΙΙΙ.
Exclusion Criteria
- •scoliosis, congenital heart disease, lung, liver, kidney diseases or increased intracranial pressure (ICP)
Outcomes
Primary Outcomes
Patients numbers of obese parturient complications
Time Frame: 2 years
Patients numbers of emergency, fetal macrosomia, gestational diabetes mellitus (GMD), CS history, fetal distress, elderly parturient women(≥35 years), prenatal fever, arrhythmias, abnormalities of the heart, hypertension(pre-eclampsia), multiple pregnancy, precious child, amniotic fluid abnormality, amout of bleeding, neonate Apgar's Score(1min), Apgar's Score(5min), and patients numbers of EA, GA, PACU (Postanesthesia Care Unit ) and ICU (Intensive Care Unit) for duration of hospital stay and anesthesia puncture times with 5\>n≥3 and n≥5 in three groups included non-Obesity group, severe Obesity group and Morbid Obesity group were also recorded. In addition, we also recorded puncture patients numbers in sitting position for all groups.