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Clinical Trials/NCT03853889
NCT03853889
Unknown
N/A

Evaluation of the Effect of Epidural Anesthesia on Optic Nerve Sheath Diameter in Patients Undergoing Cesarean Section

Abant Izzet Baysal University0 sites35 target enrollmentJune 28, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Intracranial Pressure
Sponsor
Abant Izzet Baysal University
Enrollment
35
Primary Endpoint
increase in the diameter of the optic nerve sheath after epidural anesthesia
Last Updated
6 years ago

Overview

Brief Summary

Depending on the physiology of pregnancy, the risk of increased aspiration, difficult airway, increased oxygen consumption and reduced functional residual capacity, breathing problems make general anesthesia application risky. In obstetric operations, neuraxial anesthesia is preferred because of both maternal and maternal mortality and morbidity. Epidural area has decreased due to pregnancy physiology. Previous studies have shown that the blood given to the epidural area increases the intracranial pressure by compressing the dura mater.Optic nerve diameter measurements ultrasound guided is a non-invasive and reliable method for detecting intracranial pressure increase.

In this study, aimed to compare the optic nerve sheath diameter before and after epidural anesthesia with USG.

Detailed Description

Epidural anesthesia will be performed at L2 level and sitting position in all patients. Patients will be measured and recorded for optic nerve sheath diameter at 15 min (T2), 30 min (T3) and 60 min (T4) immediately after epidural anesthesia (T0) and after epidural anesthesia.. Measurement of the optic nerve sheath diameter will be done with the help of a linear probe without applying high pressure to the eyeball while the patient is in supine position and the eyelids are closed. The optic nerve sheath diameter will be measured 3 mm beyond the optical disc. The measurements shall be applied in both transverse and sagittal planes for both eyes and the arithmetic mean of the four measured values.

Registry
clinicaltrials.gov
Start Date
June 28, 2019
End Date
December 17, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Sequential
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Murat Bilgi

Principal Investigator

Abant Izzet Baysal University

Eligibility Criteria

Inclusion Criteria

  • epidural anesthesia patients
  • 18-40 years patients
  • American Society of Anesthesiologists status I-II patients

Exclusion Criteria

  • Patients with allergy to any of the drugs to be used in the study,
  • patients with severe heart failure,
  • atrial and ventricular arrhythmias,
  • severe valve disease,
  • electrolyte disorder,
  • renal failure, preeclampsia, eclampsia

Outcomes

Primary Outcomes

increase in the diameter of the optic nerve sheath after epidural anesthesia

Time Frame: Basal(T0),Immediately after administration of epidural anesthesia(T1), after epidural anesthesia 15 min(T2), 30 min (T3),60 min (T4)

increase of intracranial pressure as a result of the administration of 20 ml of local anesthetic to the epidural area and its reflection on the diameter of the optic nerve sheath

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